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Leadership
LeadershipErik AllenChief Executive OfficerView BioKen TitlebaumChief Financial OfficerView BioBethany BellVice President, Global Business DevelopmentView BioTarika MansukhaniVice President, Global Product Management and Marketing View BioChuck McCandlessVice President, Global SalesView BioPolly M...
FAQs
ImmunoassaysWhat kind of sample type can be used with the kit I purchased?Each type of kit has been validated for the sample types indicated in its protocol. All other sample types would have to be validated internally. Please contact ALPCO's product support team for further information regardi...
TERMS OF SALE
The terms and conditions of sale (the “Terms”) contained herein apply to all quotations made and purchase orders received by American Laboratory Products Company, Ltd. (d/b/a ALPCO Diagnostics) (“ALPCO”) regarding the products sold by ALPCO (“Products”). THE ACCEPTANCE OF ANY OR ALL OF THE BUYER’S (...
Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
The Significance of Bioactive Leptin in Obesity Research
May 3, 2016 Leptin resistance is a challenging topic of conversation in obesity. It is defined by a state in which the body does not display any adapted response to high endogenous or exogenous levels of leptin while continuing to maintain excess body weight1. This may be due to a decreased uptak...
Preparing for a Successful Assay Validation
On-boarding of new assays is critical for menu expansion and revenue growth, but the validation of a new assay requires a significant investment of time and resources. Proper planning can reduce errors and delays, minimizing validation time and reducing the impact on normal operations. Below are a f...
How to Properly Collect and Handle GLP-1 Samples
We know that the proper collection and handling of samples is vital for accurately measuring GLP-1. ALPCO is here to help your lab reduce technical errors and improve assay results when running the STELLUX® Chemi Active GLP-1 (7-36) amide ELISA. Watch our video to learn how to properly collect...
12 ELISA Tips and Tricks: An Expert’s Guide to Improve Your Technique
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Managing Calprotectin as a Send Out?
While sending out for calprotectin testing offers some cost and convenience advantages when volumes are very low, bringing the process in-house allows for the opportunity to control costs, turnaround time, and quality. Considering costs and potential revenue, the volume at which in-house calprotecti...
Choosing the Relevant GLP-1 Species to Study
  A better understanding of incretins has led to tremendous therapeutic advances in the field of type 2 diabetes1. These hormones are released from the gut in response to food ingestion and lead to the stimulation of pancreatic β-cells which then release insulin in a glucose-concentration de...
ALPCO Releases a New Broad Range Periostin ELISA
ALPCO is now offering a new broad range Periostin ELISA that has been optimized to detect all known splicing forms of human periostin. The Periostin ELISA is highly characterized with a full validation package, and offers great reproducibility and precision. Not only are all standards and controls i...
Complement System TCC and C4d ELISAs Now Available
ALPCO is pleased to announce the availability of two new immunoassays to measure complement system activation, the Complement C4d ELISA and the Terminal Complement Complex (TCC) ELISA.The complement system plays an essential role in acute and chronic inflammation, in immune response to infection...
[Infographic] Alternative NAFLD and NASH Screening Methods
Download our infographic to understand the prevalence of NAFLD and NASH, as well as how biomarkers can serve as alternative NAFLD and NASH screening methods.   Download Now Estimated Global Prevalence of NAFLD Research confirms that nonalcoholic fatty liver disease (NAFLD) has an es...
GeneProof PCR Panel for Sexually Transmitted Infections
What are Sexually Transmitted Infections (STIs)? STIs, or sexually transmitted diseases (STDs), are those most often transmitted through sexual contact, but can also be transmitted to children from infected mothers during pregnancy, childbirth, and breastfeeding.1 There are over 20 different ...
DYNEX DS2® 2-Plate ELISA Processing System
ALPCO is partnering with DYNEX to provide clinical, research, and industrial laboratories with a compact, fully-automated ELISA system capable of processing two plates simultaneously.  The DYNEX DS2® is dynamic, precise, and cost-effective. Advanced Automation to Streamline Workflow Designed f...
The Impact of Adiponectin in NAFLD and NASH Research
Date: March 7, 2017 Lately, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) have been widely discussed in both the clinical and research communities. Some of the focus has been related to alternative research methods that can improve diagnostic and monitoring meth...
Insulin Resistance: Root Causes, Detection, and Prevention
The Diabetes Pandemic According to the U.S. Centers for Disease Control (CDC) and the World Health Organization, more than 34 million Americans and 422 million people worldwide have diabetes.1,2 90 to 95% of people with diabetes have type 2.1 The National Institute of Diabetes and Digestive and K...
DYNEX DSX® 4-Plate ELISA Processing System
ALPCO is partnering with DYNEX to provide laboratories with a fully-automated ELISA system capable of processing four plates simultaneously.  The DYNEX DSX® is designed to mimic ELISA accuracy without the hands-on labor, time, and cost previously required. Laboratories can take advantage of the ...
Toxicology
Drug-Induced Organ Injury Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in pre...
The Impact of DPP-4 on Active GLP-1 Preanalytical Variability
Active glucagon-like peptide-1 (active GLP-1) is an incretin hormone known for its pivotal role in the regulation of insulin and glucagon secretion1,2. However, research has demonstrated that the accurate quantification of active GLP-1 is difficult to achieve and has led to the widespread inability ...
6 Tips for Improving Chemiluminescence ELISA Precision
Chemiluminescence ELISA technology offers enhanced sensitivity with a very broad dynamic range. However, consistency in assay technique is especially important to ensure optimal performance from day-to-day and operator-to-operator. The following six tips may help to improve intra-assay and inter-ass...
How DPP-4 Complicates Measuring GLP-1 Accurately
We know that the proper collection and handling of samples is vital for eliminating analytical variability and improving accuracy when measuring active GLP-1 (7-36) amide. ALPCO is here to help your lab reduce technical errors and improve assay results when running the STELLUX® Chemi Active GLP-1...
Role of IGF-1 in the Growth Hormone/IGF Axis
The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasin...
Understanding the Role of Energy Homeostasis in Diabetes
Introduction The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and the...