The Alpha 1 Microglobulin ELISA is for the quantitative determination of alpha-1-Microglobulin in Serum, Plasma and Urine. For research use only. Not for use in diagnostic procedures.
Alpha 1 Microglobulin, a glycoprotein heterogeneous in charge, was reported to occur both as a monomer with 31kDa but also as a polymer with 90 kDa in a covalent binding with one of the two alpha chains of the monomeric Immunoglobulin A. Alpha-1-Mikroglobulin is produced in the liver and is a protein with a small molecular weight. These proteins are metabolised in the kidneys and in a healthy person, only minor amounts can be detected in urine. If the glomerular filtration rate is limited, then the increase of Alpha-1-Microglobulin is seen in serum. If the relationship between the total sum of Albumin-IgG, Alpha-1-Microglobulin in comparison to the total protein in urine is disturbed, then this indicates a prerenal protinuria.
Species
Human
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
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