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Endocrinology

Vasopressin: An Important Biomarker for Water Metabolism & Sleep Research
April 21, 2023

Vasopressin: An Important Biomarker for Water Metabolism & Sleep Research

ALPCO is pleased to announce the addition of two new radioimmunoassays (RIA) to measure vasopressin. The Vasopressin RIA and the Vasopressin Direct RIA. Both assays were originally developed by BÜHLMANN Laboratories. After optimization for greater ease-of-use, they are now offered by NovoLytiX GmbH of Switzerland. ALPCO is proud to be the exclusive distributor for the Vasopressin RIA and Va...
Iron Regulation and Homeostasis: Kits to Study Regulatory Proteins
March 25, 2022

Iron Regulation and Homeostasis: Kits to Study Regulatory Proteins

Iron Homeostasis Iron is a trace element required for several critical cellular processes. Too little iron (anemia) or too much iron (iron overload) can be harmful. While there is no known mechanism for the controlled excretion of excess iron, a handful of regulatory proteins control the absorption, transport, and storage of iron to maintain homeostasis.1,2 ALPCO offers several kits for the ...
An Accurate Solution to the Challenges with Measuring GLP-1
July 31, 2018

An Accurate Solution to the Challenges with Measuring GLP-1

Glucagon-like peptide-1 (GLP-1) is a gut hormone which plays an essential role in insulin secretion and glucose homeostasis1. While GLP-1 has become central to many metabolic disease research programs, various GLP-1 ELISA kits currently available on the market have been failing to meet the needs of researchers1-5. Therefore, measuring total and active levels of GLP-1 is difficult for many labs2...
Endocrine Disrupting Chemicals and Biomarkers of EDC
October 12, 2016

Endocrine Disrupting Chemicals and Biomarkers

Introduction Humans and the environment are exposed to numerous chemicals every day1. Each year, about 2,000 new chemicals are manufactured in the U.S.2. Research findings over the years have shown how some chemicals known as endocrine disrupting chemicals (EDCs) can interact with the endocrine system, disrupt homeostasis, and lead to issues such as obesity and sterility1. As a result, endocri...
Regulating Endocrine Disrupting Chemicals
September 27, 2016

Regulating Endocrine Disrupting Chemicals in Consumer Products

Date: September 27, 2016 Author: Andrea Tarbet, Product Marketing Associate at ALPCO From cosmetics to water bottles, endocrine disrupting chemicals (EDCs) have surfaced in our everyday lives. EDCs are compounds that can interfere with the endocrine system’s ability to help an organism develop, grow, reproduce, and maintain overall homeostasis1.  Since EDCs are found nearly everywhere, we...
ALPCO Releases a New Broad Range Periostin ELISA
June 7, 2016

ALPCO Releases a New Broad Range Periostin ELISA

ALPCO is now offering a new broad range Periostin ELISA that has been optimized to detect all known splicing forms of human periostin. The Periostin ELISA is highly characterized with a full validation package, and offers great reproducibility and precision. Not only are all standards and controls included with the kit, but it can be automated, making the assay both cost effective and flexible ...
How Runners' High and Leptin Play a Role in Metabolism
April 6, 2016

How Runners' High and Leptin Play a Role in Metabolism

  As a runner, I’ve long been intrigued by what gets me high during my runs. Endorphins, you say? Yes, I’m well aware of those and bless those endorphins. But, I have to say, there’s nothing quite as satiating as a good run and as a scientist by training, I was convinced that there was more to that feeling than endorphins. Turns out, there is. It wasn’t too long ago that I came acros...
Physiological Actions of Natriuretic Peptides
March 15, 2016

Physiological Actions of Natriuretic Peptides

Introduction Humans have at least 50 discovered hormones managing vital biological functions in the body. These hormones are produced by the body’s organs and glands. Natriuretic peptides (NPs) are structurally related hormones synthesized and released from the heart, including atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Due to some of the physiological actions of nat...
Role of IGF-1 in the Growth Hormone/IGF Axis
January 6, 2015

Role of IGF-1 in the Growth Hormone/IGF Axis

The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasing Hormone (GHRH) at the hypothalamus.   Insulin-like Growth Factors & Binding Pr...