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Rat Liver Fatty Acid Binding Protein ELISA (Rat L-FABP ELISA)Catalog #: 41-LFART-E01
Sensitivity: 12.5 ng/mL
Range: 12.5-400 ng/mL
Sample Types: Plasma, Serum
Sample Size(s): 96 Wells
Detection: Colorimetric -
Adipocyte Fatty Acid Binding Protein ELISA (AFABP ELISA)
Catalog #: 32-5181
Sensitivity: 0.1 ng/mL
Range: 0.5 - 25 ng/mL
Sample Types: Cell Culture, Plasma, Serum
Sample Size(s): 96 Wells
Detection: Colorimetric -
Rat Resistin ELISA
Catalog #: 32-5179
Sensitivity: 0.05 ng/mL
Range: 0.25 - 20 ng/mL
Sample Types: Cell Culture, Serum
Sample Size(s): 96 Wells
Detection: Colorimetric
Clinical Research
New: Calprotectin Immunoturbidimetric Assay will take your testing to the next level. Learn more.ALPCO has been serving the needs of clinical researchers and clinical diagnostics labs for over 30 years, and we now offer a broad product menu of proprietary automated sample-to-answer platforms. We’re ...
Platforms
Our platforms offer walk-away, sample-to-answer solutions for life science research, clinical research, and diagnosticsALPCO is a global leader in platforms for immunodiagnostics and molecular diagnostics. Our proprietary automated sample-to-answer solutions provide efficiency and ease-of-use for th...
Multiplex Biomarker Instrumentation
Discover Automated Multiplex Testing to Simplify Batch AnalysisALPCO has partnered with DYNEX® Technologies to leverage the DYNEX Multiplier® powered by SmartPlex® technology to fully automate multiplex analysis of novel protein biomarkers.DYNEX Multiplier® Automated Chemiluminescence AnalyzerThe DY...
Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Adipokines and Adipose Tissue-Liver Crosstalk in Energy Metabolism
Research over the past several decades examining adipokines and adipose tissue-liver crosstalk in energy metabolism has revealed that adipose tissue is a very important metabolically active endocrine organ1. White, brown, and beige adipose tissue generate and secrete adipokines, such as adiponectin ...
Featured Biomarkers from A to Z
This handout briefly describes the role of several important hormones measured in research.
Heart Disease Biomarkers in Diabetes Research
Introduction
Cardiovascular disease (CVD) encompasses a constellation of diseases related to the heart and circulatory system. Despite efforts to understand and combat CVD complications from diabetes, 65% of diabetics will pass away from cardiovascular issues1. Part 2 of The Common Denominator eBoo...
Researching the Role of Gut Permeability in NAFLD
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A growing amount of research demonstrates that communication between the gut microbiota and liver is vital for the regulation of energy metabolism1,2. As a result, scientists are further...
Insulin Resistance: Root Causes, Detection, and Prevention
The Diabetes Pandemic
According to the U.S. Centers for Disease Control (CDC) and the World Health Organization, more than 34 million Americans and 422 million people worldwide have diabetes.1,2 90 to 95% of people with diabetes have type 2.1 The National Institute of Diabetes and Digestive and K...
Celebrating Diabetes Research
In honor of scientists and researchers in the field of diabetes, we've compiled a partial list of their 2023 published work. These publications aren't just studies; they're milestones on the path to a healthier future, made possible by their dedication.
What makes this list so ...
Role of IGF-1 in the Growth Hormone/IGF Axis
The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasin...
Physiological Actions of Natriuretic Peptides
Introduction
Humans have at least 50 discovered hormones managing vital biological functions in the body. These hormones are produced by the body’s organs and glands. Natriuretic peptides (NPs) are structurally related hormones synthesized and released from the heart, including atrial natriuretic p...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin
Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...
Endocrine Disrupting Chemicals and Biomarkers
Introduction
Humans and the environment are exposed to numerous chemicals every day1. Each year, about 2,000 new chemicals are manufactured in the U.S.2. Research findings over the years have shown how some chemicals known as endocrine disrupting chemicals (EDCs) can interact with the endocrine sys...
Emerging Biomarker Research in NAFLD and NASH
Nonalcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease in the western hemisphere affecting 1 in 3 adults and 1 in 10 children1. Today, liver biopsies are the only gold standard for precise diagnosis of NAFLD2. Because of this, there are tremendous efforts on the ...
Obesity Induced Adipose Tissue Dysfunction and NAFLD
Obesity is a known risk factor for developing metabolic diseases such as non-alcoholic fatty liver disease (NAFLD)1. An increasing amount of evidence shows that obesity induced adipose tissue dysfunction and NAFLD development are closely related2. Obesity induced changes to adipokine secretion can h...
Organ Crosstalk in Obesity and NAFLD
The liver is vital to various metabolic functions including lipid and glucose metabolism. In order to maintain homeostasis, efficient gut-liver and adipose tissue-liver communications are needed1,2. Research indicates that obesity induced dysfunctions within these crosstalks can lead to imbalances i...
Understanding Exocrine Pancreatic Insufficiency
Pancreatic Elastase (PE) Testing for Determination of Exocrine Pancreatic Insufficiency (EPI)
Advantages of ALPCO PE Testing for Determination of EPI
• No interference from PERT
• Single sample collection without dietary restriction
• Detection of both CELA3A and CELA3B isoforms
• Compatibi...
ELISAs for CHO Host Cell Proteins
Chinese Hamster Ovary (CHO) cells are the most dependable and most popular host cells for the industrial production of biotherapeutics. They are stable cell lines that are adaptable to a wide range of culture conditions and routinely produce very high protein and antibody yields. More importantly,...
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
ALPCO's New FDA Cleared 25-OH Vitamin D Total ELISA Provides Option for Hospitals and Smaller Clinical Labs to Bring Affordable Testing In-House
ALPCO announced in a press release on January 22, 2014 that their test portfolio for clinical and hospital laboratory customers has expanded to include a new FDA 510(k) cleared 25-OH Vitamin D Total ELISA.
The growth in 25-OH Vitamin D testing has been a challenge for clinical and hospital labora...
Complement System Solutions for Drug Development and Clinical Research
Datasheet: Complement System Immunoassays
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The complement system is essential to innate immunity which protects from chronic, autoimmune, and infectious disease. There are three distinct pathways of complement activation: classical, lectin/MBL, and alternative. Each leads...
How Should We Define Vitamin D Deficiency?
Date: July 21, 2015
Author: Bethany Bell, PhD; Senior Product Manager at ALPCO
Dr. Anders Berg presented at the Northeast Laboratory Conference in October 2014 regarding a much debated topic: vitamin D deficiency and how this should be defined. Dr. Berg referenced over one thousand studies, re...
Understanding the Role of Energy Homeostasis in Diabetes
Introduction
The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and the...