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Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Clinical Research
New: Calprotectin Immunoturbidimetric Assay will take your testing to the next level. Learn more.ALPCO has been serving the needs of clinical researchers and clinical diagnostics labs for over 30 years, and we now offer a broad product menu of proprietary automated sample-to-answer platforms. We’re ...
Platforms
Our platforms offer walk-away, sample-to-answer solutions for life science research, clinical research, and diagnosticsALPCO is a global leader in platforms for immunodiagnostics and molecular diagnostics. Our proprietary automated sample-to-answer solutions provide efficiency and ease-of-use for th...
ELISA Instrumentation
Automate ELISA Testing to Improve Performance and Productivity Shifting from manual ELISA processing to automation helps reduce variability and improve analytical performance. ALPCO offers automation to optimize workflow, capacity, and productivity.DYNEX DS2® 2-Plate ELISA Processing SystemCompact....
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...
Therapeutic Drug Monitoring of Biosimilars in Autoimmune Diseases
Anti-TNF-alpha biologics have been proven to be effective treatments for autoimmune diseases such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD)1. Rising healthcare costs as well as patent expirations, however, have prompted the development of biosimilars, such as the infliximab b...
An Accurate Solution to the Challenges with Measuring GLP-1
Glucagon-like peptide-1 (GLP-1) is a gut hormone which plays an essential role in insulin secretion and glucose homeostasis1. While GLP-1 has become central to many metabolic disease research programs, various GLP-1 ELISA kits currently available on the market have been failing to meet the needs of ...
The Generation and Function of Active GLP-1
The Generation and Function of Active GLP-1 Active glucagon-like peptide-1 (GLP-1) is a member of the incretin hormone family and is generated as a result of post translational modifications during proglucagon processing1,2. Active GLP-1 plays a key role in the incretin effect and is vital for main...
A Guide to STELLUX® Chemiluminscence ELISAs: An Infographic
Today, multiple immunoassay platforms exist, providing scientists and clinicians with the means to measure a variety of biomarkers1,2,3. However, research indicates some immunoassay platforms have limitations that can inhibit progress in the laboratory4,5,6. In an effort to provide researchers with ...
Now Available: 510(k) Cleared Fecal Calprotectin ELISA
ALPCO received 510(k) clearance from the US FDA for its new fecal Calprotectin Chemiluminescence ELISA test. The ALPCO Calprotectin Chemiluminescence ELISA’s superior clinical accuracy will enable clinical laboratories to provide the most accurate results to gastroenterologists facing the cha...
Why Clinical Specificity is Important for FDA Cleared Fecal Calprotectin Tests
The Importance of Clinical Specificity: A Review of FDA Cleared Fecal Calprotectin Tests Download Selecting the right fecal calprotectin test for your clinical laboratory to run in-house or send out can be a difficult task to accomplish, especially when there are multiple FDA cleared options...
Managing Calprotectin as a Send Out?
While sending out for calprotectin testing offers some cost and convenience advantages when volumes are very low, bringing the process in-house allows for the opportunity to control costs, turnaround time, and quality. Considering costs and potential revenue, the volume at which in-house calprotecti...
Enhance Your Lab’s Molecular GI Portfolio
Molecular GI testing for bacteria such as salmonella, vibrio, and E. coli, and viral pathogens including norovirus and rotavirus, is instrumental in the diagnosis and treatment of infection and dysbiosis. In addition, many gastrointestinal disorders often require protein biomarker tests to aid in ac...
GI Testing
Calprotectin Chemiluminescence ELISA (80-CALPHU-CH01) The Calprotectin Chemiluminescence ELISA is an in vitro diagnostic chemiluminescent assay intended for the quantitative measurement of fecal calprotectin, a neutrophilic protein that is a marker of intestinal mucosal inflammation, in human sto...
Immunoassays for Intact and Total Proinsulin
ALPCO is pleased to announce the availability of two new immunoassays, the Intact Proinsulin ELISA and the Total Proinsulin ELISA.  Proinsulin is a precursor molecule produced by pancreatic ß-cells, primarily in response to glucose, that is cleaved equally into insulin and c-peptide. Elevated le...
Iron Regulation and Homeostasis: Kits to Study Regulatory Proteins
Iron Homeostasis Iron is a trace element required for several critical cellular processes. Too little iron (anemia) or too much iron (iron overload) can be harmful. While there is no known mechanism for the controlled excretion of excess iron, a handful of regulatory proteins control the absorpti...
AutoPlex Automated Multiplex Biomarker Analysis
ALPCO’s automated multiplex assay, AutoPlex GI Panel, provides sensitive and accurate measurement of up to 5 GI biomarkers in human stool samples. The panel combines the workflow advantages of multiplexing with the proven reliability of traditional chemiluminescence sandwich immunoassays to enable b...
Celebrating Diabetes Research
In honor of scientists and researchers in the field of diabetes, we've compiled a partial list of their 2023 published work. These publications aren't just studies; they're milestones on the path to a healthier future, made possible by their dedication.  What makes this list so ...
Product Data: Insulin Chemiluminescence ELISA
ALPCO’s Insulin Chemiluminescence ELISA detects insulin at levels as low as 20 pg/mL in human serum, plasma, and β-islet tissue culture supernatants, without cross-reactivity to human intact proinsulin, mouse insulin, or rat insulin.
Product Data: Rodent Insulin Chemiluminescence ELISA
The STELLUX® Rodent Insulin ELISA provides the flexibility to run both mouse and rat samples on the same plate with minimal to no dilution and a short two hour incubation.
Product Data: Active GLP-1 (7-36) amide Chemiluminescence ELISA
ALPCO’s Active GLP-1 (7-36) amide Chemiluminescence ELISA accurately measures the major biologically active circulating form of GLP-1.1,2 This well-characterized assay provides high analytical sensitivity, a short incubation time, and measures active GLP-1 (7-36) amide in fasted and fed samples.
ALPCO Releases STELLUX® Chemiluminescent Human Intact Proinsulin ELISA
ALPCO announced in a press release on February 18, 2014 that the company has launched their new STELLUX® Chemiluminescent Human Intact Proinsulin ELISA, the latest assay to be launched in the company’s STELLUX® Chemiluminescent product line. The new Human Intact Proinsulin ELISA features a broad dyn...
ALPCO to Feature New STELLUX® Chemi Active GLP-1 (7-36) amide ELISA and Young Investigators Travel Grant Program at ADA’s 78th Scientific Sessions
June 19, 2018 ALPCO, a leading producer of research and clinical immunoassays, announced it will showcase its new STELLUX® Chemi Active GLP-1 (7-36) amide ELISA at the American Diabetes Association’s 78th Scientific Sessions June 23-25, 2018 in Orlando, FL.  This new addition to the STELLUX® Chem...