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About Us
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Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Responsibility
ALPCO’s Diabetes Research Travel GrantALPCO strives to provide scientists and healthcare professionals with robust tools for their research and clinical diagnostic endeavors. We understand that championing extraordinary discoveries requires extraordinary efforts, and support. We are proud to continu...
Life Science Research
Moving your life science research toward breakthroughs with reagents and walk-away, sample-to-answer solutionsWhether you’re doing basic or translational life science research, you need ready access to the platforms, assays, products, and other tools that are essential to your work. ALPCO has been d...
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
Complement System Webinar
Dr. Jörgen Wieslander from our partner, Euro Diagnostica, discusses functional assessment of all three pathways of the complement system. https://www.youtube.com/watch?v=afJwUGoN99M
ALPCO's New FDA Cleared 25-OH Vitamin D Total ELISA Provides Option for Hospitals and Smaller Clinical Labs to Bring Affordable Testing In-House
ALPCO announced in a press release on January 22, 2014 that their test portfolio for clinical and hospital laboratory customers has expanded to include a new FDA 510(k) cleared 25-OH Vitamin D Total ELISA. The growth in 25-OH Vitamin D testing has been a challenge for clinical and hospital labora...
ALPCO Releases New Chemiluminescent Human C-peptide ELISA
ALPCO announced the launch of its new STELLUX® Chemiluminescent Human C-peptide ELISA on December 5, 2014. This highly characterized assay measures C-peptide requiring only 50 µL of human serum, plasma or cell culture supernatant. The ELISA exhibits greater sensitivity and a broader dynamic range co...
Complement System Solutions for Drug Development and Clinical Research
Datasheet: Complement System Immunoassays Download The complement system is essential to innate immunity which protects from chronic, autoimmune, and infectious disease. There are three distinct pathways of complement activation: classical, lectin/MBL, and alternative. Each leads...
Role of IGF-1 in the Growth Hormone/IGF Axis
The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasin...
Vitamin D Metabolism and Function
Understanding Vitamin D Metabolism & Function Vitamin D is a steroid hormone involved in the intestinal absorption of calcium and the regulation of calcium homeostasis, bone differentiation and immune response. The term "vitamin D" refers to several different forms of this vitamin. ...
Bone Metabolism: The Cycle of Bone Growth and Resorption
Bone metabolism is a continual cycle of bone growth and resorption that is carefully orchestrated by the dynamic relationship between osteoclasts, osteoblasts and an array of hormonal and regulatory influences. The relative levels of these signaling molecules dictate whether healthy, balanced bo...
Toxicology
Drug-Induced Organ Injury Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in pre...
How Should We Define Vitamin D Deficiency?
Date: July 21, 2015 Author: Bethany Bell, PhD; Senior Product Manager at ALPCO Dr. Anders Berg presented at the Northeast Laboratory Conference in October 2014 regarding a much debated topic: vitamin D deficiency and how this should be defined. Dr. Berg referenced over one thousand studies, re...
CisBio's Chromoa® Chromogranin A ELISA
Chromoa® The Chromoa® Chromogranin A ELISA from Cisbio Bioassays is for the quantitative determination of CgA in serum and plasma. The patented monoclonal detection system provides superior specificity, sensitivity and reproducibility to determine elevated serum CgA levels. Above all, the hook effe...
Understanding the Role of Energy Homeostasis in Diabetes
Introduction The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and the...
ALPCO and Cisbio US, Inc. Announce Sales and Distribution Agreement
Date: July 1, 2015 ALPCO is pleased to announce a strategic account sales and distribution agreement with Cisbio US, Inc. Cisbio will now have exclusive access to ALPCO’s high quality STELLUX® Chemiluminescence and colorimetric Diabetes and Obesity assay portfolio in order to provide these produc...
Simplify Stool Sample Processing
Introduction We understand the challenges facing lab managers and directors who need to continuously improve workflow efficiency and implement new tests and technologies to be competitive. Our unique extraction method can be used with a portfolio of targeted stool markers. This allows your lab to s...
Measuring Pancreatic Elastase to Diagnose Pancreatic Disease
Many digestive system disorders and diseases can  present similar types of symptoms including bloating, diarrhea, constipation, and weight gain/loss. In an effort to rule in or rule out the presence of one disease or the absence of another, clinicians will often turn to clinically approved stool-bas...
Heart Disease Biomarkers in Diabetes Research
Introduction Cardiovascular disease (CVD) encompasses a constellation of diseases related to the heart and circulatory system. Despite efforts to understand and combat CVD complications from diabetes, 65% of diabetics will pass away from cardiovascular issues1. Part 2 of The Common Denominator eBoo...
Physiological Actions of Natriuretic Peptides
Introduction Humans have at least 50 discovered hormones managing vital biological functions in the body. These hormones are produced by the body’s organs and glands. Natriuretic peptides (NPs) are structurally related hormones synthesized and released from the heart, including atrial natriuretic p...
Stool-Based Biomarkers to Differentiate Between IBD and IBS
What are IBD and IBS? Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are two different gastrointestinal tract issues affecting millions of people every day. Although there is some overlap between symptoms of IBD and IBS, differences still remain in regards to pathologies, risks...
Early Detection of Diabetic Kidney Disease with Biomarkers
Introduction Over one third of diabetics will develop diabetic kidney disease (DKD) in their lifetime1. Despite the large amount of diabetics suffering from DKD, current methods for measuring and tracking kidney function may not be specific enough for diabetic systems2,3. Part III of The Common ...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...