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Responsibility
ALPCO’s Diabetes Research Travel GrantALPCO strives to provide scientists and healthcare professionals with robust tools for their research and clinical diagnostic endeavors. We understand that championing extraordinary discoveries requires extraordinary efforts, and support. We are proud to continu...
Clinical Research
New: Calprotectin Immunoturbidimetric Assay will take your testing to the next level. Learn more.ALPCO has been serving the needs of clinical researchers and clinical diagnostics labs for over 30 years, and we now offer a broad product menu of proprietary automated sample-to-answer platforms. We’re ...
Platforms
Our platforms offer walk-away, sample-to-answer solutions for life science research, clinical research, and diagnosticsALPCO is a global leader in platforms for immunodiagnostics and molecular diagnostics. Our proprietary automated sample-to-answer solutions provide efficiency and ease-of-use for th...
Multiplex Allergy
MADx Multiplex Allergy Assays & InstrumentationALPCO is the exclusive North American distributor for the MADx ALEX2 platform for multiplex IgE allergy detection and the FOX platform for detection of IgG-mediated food intolerance.MAX 45k for Automated Sample ProcessingThe MAX 45K is a fully aut...
Understanding the Role of Energy Homeostasis in Diabetes
Introduction The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and the...
Heart Disease Biomarkers in Diabetes Research
Introduction Cardiovascular disease (CVD) encompasses a constellation of diseases related to the heart and circulatory system. Despite efforts to understand and combat CVD complications from diabetes, 65% of diabetics will pass away from cardiovascular issues1. Part 2 of The Common Denominator eBoo...
Choosing the Relevant GLP-1 Species to Study
  A better understanding of incretins has led to tremendous therapeutic advances in the field of type 2 diabetes1. These hormones are released from the gut in response to food ingestion and lead to the stimulation of pancreatic β-cells which then release insulin in a glucose-concentration de...
Adipokines and Adipose Tissue-Liver Crosstalk in Energy Metabolism
Research over the past several decades examining adipokines and adipose tissue-liver crosstalk in energy metabolism has revealed that adipose tissue is a very important metabolically active endocrine organ1. White, brown, and beige adipose tissue generate and secrete adipokines, such as adiponectin ...
The Generation and Function of Active GLP-1
The Generation and Function of Active GLP-1 Active glucagon-like peptide-1 (GLP-1) is a member of the incretin hormone family and is generated as a result of post translational modifications during proglucagon processing1,2. Active GLP-1 plays a key role in the incretin effect and is vital for main...
Insulin Resistance: Root Causes, Detection, and Prevention
The Diabetes Pandemic According to the U.S. Centers for Disease Control (CDC) and the World Health Organization, more than 34 million Americans and 422 million people worldwide have diabetes.1,2 90 to 95% of people with diabetes have type 2.1 The National Institute of Diabetes and Digestive and K...
Featured Biomarkers from A to Z
This handout briefly describes the role of several important hormones measured in research.
Celebrating Diabetes Research
In honor of scientists and researchers in the field of diabetes, we've compiled a partial list of their 2023 published work. These publications aren't just studies; they're milestones on the path to a healthier future, made possible by their dedication.  What makes this list so ...
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
ALPCO to Feature New STELLUX® Chemi Active GLP-1 (7-36) amide ELISA and Young Investigators Travel Grant Program at ADA’s 78th Scientific Sessions
June 19, 2018 ALPCO, a leading producer of research and clinical immunoassays, announced it will showcase its new STELLUX® Chemi Active GLP-1 (7-36) amide ELISA at the American Diabetes Association’s 78th Scientific Sessions June 23-25, 2018 in Orlando, FL.  This new addition to the STELLUX® Chem...
Proinsulin, Insulin and Beta Cell Dysfunction
UBC Professor Bruce Verchere, PhD discusses the significance of proinsulin and insulin as biomarkers to probe beta cell dysfunction. https://www.youtube.com/watch?v=HM5FN3D5VxI
Role of IGF-1 in the Growth Hormone/IGF Axis
The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasin...
Bone Metabolism: The Cycle of Bone Growth and Resorption
Bone metabolism is a continual cycle of bone growth and resorption that is carefully orchestrated by the dynamic relationship between osteoclasts, osteoblasts and an array of hormonal and regulatory influences. The relative levels of these signaling molecules dictate whether healthy, balanced bo...
Toxicology
Drug-Induced Organ Injury Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in pre...
Simplify Stool Sample Processing
Introduction We understand the challenges facing lab managers and directors who need to continuously improve workflow efficiency and implement new tests and technologies to be competitive. Our unique extraction method can be used with a portfolio of targeted stool markers. This allows your lab to s...
New Stool-Based Gastroenterology Assays and Extraction Method Can Improve Lab Sample Processing Time By Up To 86%
Date: January 26, 2016 ALPCO recently launched a new panel of 13 stool-based gastroenterology assays that are all compatible with one single extraction step. The unique extraction method allows laboratories to improve their sample processing time by up to 86% by extracting one sample for up to 13...
Stool-Based Biomarkers to Differentiate Between IBD and IBS
What are IBD and IBS? Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are two different gastrointestinal tract issues affecting millions of people every day. Although there is some overlap between symptoms of IBD and IBS, differences still remain in regards to pathologies, risks...
How Runners' High and Leptin Play a Role in Metabolism
  As a runner, I’ve long been intrigued by what gets me high during my runs. Endorphins, you say? Yes, I’m well aware of those and bless those endorphins. But, I have to say, there’s nothing quite as satiating as a good run and as a scientist by training, I was convinced that there was more ...
Early Detection of Diabetic Kidney Disease with Biomarkers
Introduction Over one third of diabetics will develop diabetic kidney disease (DKD) in their lifetime1. Despite the large amount of diabetics suffering from DKD, current methods for measuring and tracking kidney function may not be specific enough for diabetic systems2,3. Part III of The Common ...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...