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PRIVACY POLICY
This privacy policy discloses the privacy practices for alpco.com. This privacy policy applies solely to information collected by this website. It will notify you of the following: What personally identifiable information is collected from you through the website, how it is used and with whom it ...
Diagnostic Testing in GI Health
 60 to 70 million Americans are affected by gastrointestinal (GI) diseases and disorders each year. The estimated annual U.S. cost associated with GI disorders is over 140 billion dollars. Gl diseases and disorders can have a significant impact on quality of life, often contributing to anxiety ...
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
Toxicology
Drug-Induced Organ Injury Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in pre...
Understanding the Role of Energy Homeostasis in Diabetes
Introduction The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and the...
Heart Disease Biomarkers in Diabetes Research
Introduction Cardiovascular disease (CVD) encompasses a constellation of diseases related to the heart and circulatory system. Despite efforts to understand and combat CVD complications from diabetes, 65% of diabetics will pass away from cardiovascular issues1. Part 2 of The Common Denominator eBoo...
The Changing Roles of Bone Remodeling Biomarkers
Introduction Bones are traditionally known for their support, protection and movement properties, as well as their role in the processes of mineral balance and blood cell production. Research supports that bones do more than they were originally recognized for. Previous research investigating osteo...
Class IA PI3K Inhibitor Cancer Therapies
Date: August 16, 2016 Author: Andrea Tarbet, Product Marketing Associate at ALPCO Bruton’s tyrosine kinase (BTK) inhibitors are not the only kinase inhibitors to enter the fight against B cell cancers. Since there are numerous subtypes of Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL), p...
PI3K Delta Signaling in Rheumatoid Arthritis
Date: September 6, 2016 Author: Andrea Tarbet, Product Marketing Associate at ALPCO Signaling pathways dictate the differentiation, activation, and functions of immune cells.  Even the slightest problem in one cell signaling pathway can transform the immune system and turn it against the body,...
Regulating Endocrine Disrupting Chemicals in Consumer Products
Date: September 27, 2016 Author: Andrea Tarbet, Product Marketing Associate at ALPCO From cosmetics to water bottles, endocrine disrupting chemicals (EDCs) have surfaced in our everyday lives. EDCs are compounds that can interfere with the endocrine system’s ability to help an organism develop...
Emerging Biomarker Research in NAFLD and NASH
Nonalcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease in the western hemisphere affecting 1 in 3 adults and 1 in 10 children1.  Today, liver biopsies are the only gold standard for precise diagnosis of NAFLD2. Because of this, there are tremendous efforts on the ...
Adipokines and Adipose Tissue-Liver Crosstalk in Energy Metabolism
Research over the past several decades examining adipokines and adipose tissue-liver crosstalk in energy metabolism has revealed that adipose tissue is a very important metabolically active endocrine organ1. White, brown, and beige adipose tissue generate and secrete adipokines, such as adiponectin ...
Obesity Induced Adipose Tissue Dysfunction and NAFLD
Obesity is a known risk factor for developing metabolic diseases such as non-alcoholic fatty liver disease (NAFLD)1. An increasing amount of evidence shows that obesity induced adipose tissue dysfunction and NAFLD development are closely related2. Obesity induced changes to adipokine secretion can h...
Researching the Role of Gut Permeability in NAFLD
[playlist images="false" artists="false" tracklist="false" ids="4600"] A growing amount of research demonstrates that communication between the gut microbiota and liver is vital for the regulation of energy metabolism1,2. As a result, scientists are further...
How to Properly Collect and Handle GLP-1 Samples
We know that the proper collection and handling of samples is vital for accurately measuring GLP-1. ALPCO is here to help your lab reduce technical errors and improve assay results when running the STELLUX® Chemi Active GLP-1 (7-36) amide ELISA. Watch our video to learn how to properly collect...
A Comparison of Colorimetric and Chemiluminescence ELISAs
Are you curious about chemiluminescence ELISAs, but not exactly sure what they are, or how to use them? Our video A Comparison of Colorimetric and Chemiluminescence ELISAs discusses how similar these two types of assays are, and how they can enhance your lab testing. Watch our video to: Lear...
Insulin Resistance: Root Causes, Detection, and Prevention
The Diabetes Pandemic According to the U.S. Centers for Disease Control (CDC) and the World Health Organization, more than 34 million Americans and 422 million people worldwide have diabetes.1,2 90 to 95% of people with diabetes have type 2.1 The National Institute of Diabetes and Digestive and K...
Vasopressin: An Important Biomarker for Water Metabolism & Sleep Research
ALPCO is pleased to announce the addition of two new radioimmunoassays (RIA) to measure vasopressin. The Vasopressin RIA and the Vasopressin Direct RIA. Both assays were originally developed by BÜHLMANN Laboratories. After optimization for greater ease-of-use, they are now offered by NovoLytiX G...
Featured Biomarkers from A to Z
This handout briefly describes the role of several important hormones measured in research.
Total IgG vs. IgG4 Testing
The use of serological testing for the detection of allergen sensitization, food intolerance, and the development of allergen tolerance is rapidly expanding. In addition to traditional IgE testing, a growing number of IgG tests are entering the market. Some tests measure total IgG, while others ...
ALPCO-GeneProof Appoints Erik M. Allen as Chief Executive Officer
SALEM, N.H. and BRNO, Czech Republic, March 30, 2023 /PRNewswire/ -- American Laboratory Products Company, Ltd. ("ALPCO", or the "Company"), a global provider of specialty diagnostic solutions, today announced the appointment of Erik M. Allen as Chief Executive Officer (CEO). Mr....