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New: Calprotectin Immunoturbidimetric Assay will take your testing to the next level. Learn more.Supporting your work with life science and clinical testing productsVIEW ALL LIFE SCIENCE PRODUCTSVIEW ALL CLINICAL DIAGNOSTIC PRODUCTS
Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Company Overview
Accuracy and Efficiency. Together.We are a leading global developer and provider of innovative molecular and immunodiagnostic products focused on Infectious and Gastroenterological Diseases.  We are a trusted partner creating value for research and clinical laboratories with high-quality, user-frien...
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ALPCO’s Diabetes Research Travel GrantALPCO strives to provide scientists and healthcare professionals with robust tools for their research and clinical diagnostic endeavors. We understand that championing extraordinary discoveries requires extraordinary efforts, and support. We are proud to continu...
Heart Disease Biomarkers in Diabetes Research
Introduction Cardiovascular disease (CVD) encompasses a constellation of diseases related to the heart and circulatory system. Despite efforts to understand and combat CVD complications from diabetes, 65% of diabetics will pass away from cardiovascular issues1. Part 2 of The Common Denominator eBoo...
Physiological Actions of Natriuretic Peptides
Introduction Humans have at least 50 discovered hormones managing vital biological functions in the body. These hormones are produced by the body’s organs and glands. Natriuretic peptides (NPs) are structurally related hormones synthesized and released from the heart, including atrial natriuretic p...
Adipokines and Adipose Tissue-Liver Crosstalk in Energy Metabolism
Research over the past several decades examining adipokines and adipose tissue-liver crosstalk in energy metabolism has revealed that adipose tissue is a very important metabolically active endocrine organ1. White, brown, and beige adipose tissue generate and secrete adipokines, such as adiponectin ...
Researching the Role of Gut Permeability in NAFLD
[playlist images="false" artists="false" tracklist="false" ids="4600"] A growing amount of research demonstrates that communication between the gut microbiota and liver is vital for the regulation of energy metabolism1,2. As a result, scientists are further...
Featured Biomarkers from A to Z
This handout briefly describes the role of several important hormones measured in research.
Celebrating Diabetes Research
In honor of scientists and researchers in the field of diabetes, we've compiled a partial list of their 2023 published work. These publications aren't just studies; they're milestones on the path to a healthier future, made possible by their dedication.  What makes this list so ...
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
Complement System Solutions for Drug Development and Clinical Research
Datasheet: Complement System Immunoassays Download The complement system is essential to innate immunity which protects from chronic, autoimmune, and infectious disease. There are three distinct pathways of complement activation: classical, lectin/MBL, and alternative. Each leads...
Early Detection of Diabetic Kidney Disease with Biomarkers
Introduction Over one third of diabetics will develop diabetic kidney disease (DKD) in their lifetime1. Despite the large amount of diabetics suffering from DKD, current methods for measuring and tracking kidney function may not be specific enough for diabetic systems2,3. Part III of The Common ...
De-escalating Inflammatory Bowel Disease Therapies
Date: June 21, 2016 Author: Andrea Tarbet, Product Marketing Associate at ALPCO Several therapies exist to help treat inflammatory bowel disease (IBD) and improve patient quality of life. However, a growing number of gastroenterologists and patients have been choosing to stop these therapies -...
Regulating Endocrine Disrupting Chemicals in Consumer Products
Date: September 27, 2016 Author: Andrea Tarbet, Product Marketing Associate at ALPCO From cosmetics to water bottles, endocrine disrupting chemicals (EDCs) have surfaced in our everyday lives. EDCs are compounds that can interfere with the endocrine system’s ability to help an organism develop...
Endocrine Disrupting Chemicals and Biomarkers
Introduction Humans and the environment are exposed to numerous chemicals every day1. Each year, about 2,000 new chemicals are manufactured in the U.S.2. Research findings over the years have shown how some chemicals known as endocrine disrupting chemicals (EDCs) can interact with the endocrine sys...
Choosing the Relevant GLP-1 Species to Study
  A better understanding of incretins has led to tremendous therapeutic advances in the field of type 2 diabetes1. These hormones are released from the gut in response to food ingestion and lead to the stimulation of pancreatic β-cells which then release insulin in a glucose-concentration de...
[Infographic] Alternative NAFLD and NASH Screening Methods
Download our infographic to understand the prevalence of NAFLD and NASH, as well as how biomarkers can serve as alternative NAFLD and NASH screening methods.   Download Now Estimated Global Prevalence of NAFLD Research confirms that nonalcoholic fatty liver disease (NAFLD) has an es...
Emerging Biomarker Research in NAFLD and NASH
Nonalcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease in the western hemisphere affecting 1 in 3 adults and 1 in 10 children1.  Today, liver biopsies are the only gold standard for precise diagnosis of NAFLD2. Because of this, there are tremendous efforts on the ...
The Impact of Adiponectin in NAFLD and NASH Research
Date: March 7, 2017 Lately, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) have been widely discussed in both the clinical and research communities. Some of the focus has been related to alternative research methods that can improve diagnostic and monitoring meth...
The Role of Bile Acids in Inflammation
Presented by: Evelyn Zöhrer, PhD; Medical University of Graz Bile acids act as emulsifiers and promote the absorption of lipids. In addition to the facilitation of digestion, bile acids are now being recognized as key players in the regulation of a myriad of metabolic processes. As such, the role...
Leveraging Non-Invasive Approaches in NAFLD and NASH Diagnosis and Clinical Research
Nonalcoholic fatty liver disease (NAFLD) / nonalcoholic steatohepatitis (NASH) is anticipated to become the next major health epidemic. NAFLD is a chronic disease ranging from fatty liver to NASH to advanced end stage liver failure. Currently, liver biopsy is the gold standard for clinical diagnosis...
Obesity Induced Adipose Tissue Dysfunction and NAFLD
Obesity is a known risk factor for developing metabolic diseases such as non-alcoholic fatty liver disease (NAFLD)1. An increasing amount of evidence shows that obesity induced adipose tissue dysfunction and NAFLD development are closely related2. Obesity induced changes to adipokine secretion can h...
Researching Therapeutic Drug Monitoring for IBD
Multiple classes of biologics are available for the treatment of inflammation associated with inflammatory bowel disease (IBD) which ultimately improves the quality of life for patients.  However, many challenges are associated with using biologics to treat IBD such as immunogenetic reactions and th...

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