This photometric Immundiagnostik assay is intended for the quantitative determination of the total oxidative status/capacity (TOS/TOC) in EDTA plasma, serum and cell culture supernatants. For research use only only. Not for use in diagnostic precedures
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
One point calibration
Sensitivity
7 umol/L
Sizes
96 Wells
Sample Types
Biological Fluids, EDTA Plasma, Plasma, Serum
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
10
An overproduction of oxygen radicals or insufficient antioxidative capacity leads to a dangerous imbalance in the organism. This starts pathological mechanisms which develop several diseases. The most important disease is the cardiovascular arterosclerosis. Beside this inflammation processes, sepsis, cancerogenesis and neurodegenerative diseases are postulated.
This is the reason why the determination of the oxidative status/oxidative stress is of fundamental importance in medical diagnosis and in research. The methods used for measurement of radical-linked effects (lipid peroxidation) up to now are very time consuming (HPLC) or reflect only breakdown products of multiple unsaturated fatty acids (TBARS).
The PerOX-Assay is fast, reliable and easy to perform. Total lipidperoxides are measured. Because of a direct correlation between oxygen radicals and lipidperoxides it is possible to measure and characterize the oxidative status/oxidative stress in biological fluids.
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