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Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Responsibility
ALPCO’s Diabetes Research Travel GrantALPCO strives to provide scientists and healthcare professionals with robust tools for their research and clinical diagnostic endeavors. We understand that championing extraordinary discoveries requires extraordinary efforts, and support. We are proud to continu...
Life Science Research
Moving your life science research toward breakthroughs with reagents and walk-away, sample-to-answer solutionsWhether you’re doing basic or translational life science research, you need ready access to the platforms, assays, products, and other tools that are essential to your work. ALPCO has been d...
Featured Biomarkers from A to Z
This handout briefly describes the role of several important hormones measured in research.
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
ALPCO Releases STELLUX® Chemiluminescent Human Intact Proinsulin ELISA
ALPCO announced in a press release on February 18, 2014 that the company has launched their new STELLUX® Chemiluminescent Human Intact Proinsulin ELISA, the latest assay to be launched in the company’s STELLUX® Chemiluminescent product line. The new Human Intact Proinsulin ELISA features a broad dyn...
ALPCO to Feature New STELLUX® Chemi Active GLP-1 (7-36) amide ELISA and Young Investigators Travel Grant Program at ADA’s 78th Scientific Sessions
June 19, 2018 ALPCO, a leading producer of research and clinical immunoassays, announced it will showcase its new STELLUX® Chemi Active GLP-1 (7-36) amide ELISA at the American Diabetes Association’s 78th Scientific Sessions June 23-25, 2018 in Orlando, FL.  This new addition to the STELLUX® Chem...
ALPCO Releases New Chemiluminescent Human C-peptide ELISA
ALPCO announced the launch of its new STELLUX® Chemiluminescent Human C-peptide ELISA on December 5, 2014. This highly characterized assay measures C-peptide requiring only 50 µL of human serum, plasma or cell culture supernatant. The ELISA exhibits greater sensitivity and a broader dynamic range co...
Complement System Solutions for Drug Development and Clinical Research
Datasheet: Complement System Immunoassays Download The complement system is essential to innate immunity which protects from chronic, autoimmune, and infectious disease. There are three distinct pathways of complement activation: classical, lectin/MBL, and alternative. Each leads...
Role of IGF-1 in the Growth Hormone/IGF Axis
The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasin...
Bone Metabolism: The Cycle of Bone Growth and Resorption
Bone metabolism is a continual cycle of bone growth and resorption that is carefully orchestrated by the dynamic relationship between osteoclasts, osteoblasts and an array of hormonal and regulatory influences. The relative levels of these signaling molecules dictate whether healthy, balanced bo...
Toxicology
Drug-Induced Organ Injury Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in pre...
CisBio's Chromoa® Chromogranin A ELISA
Chromoa® The Chromoa® Chromogranin A ELISA from Cisbio Bioassays is for the quantitative determination of CgA in serum and plasma. The patented monoclonal detection system provides superior specificity, sensitivity and reproducibility to determine elevated serum CgA levels. Above all, the hook effe...
Understanding the Role of Energy Homeostasis in Diabetes
Introduction The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and the...
ALPCO and Cisbio US, Inc. Announce Sales and Distribution Agreement
Date: July 1, 2015 ALPCO is pleased to announce a strategic account sales and distribution agreement with Cisbio US, Inc. Cisbio will now have exclusive access to ALPCO’s high quality STELLUX® Chemiluminescence and colorimetric Diabetes and Obesity assay portfolio in order to provide these produc...
Simplify Stool Sample Processing
Introduction We understand the challenges facing lab managers and directors who need to continuously improve workflow efficiency and implement new tests and technologies to be competitive. Our unique extraction method can be used with a portfolio of targeted stool markers. This allows your lab to s...
New Stool-Based Gastroenterology Assays and Extraction Method Can Improve Lab Sample Processing Time By Up To 86%
Date: January 26, 2016 ALPCO recently launched a new panel of 13 stool-based gastroenterology assays that are all compatible with one single extraction step. The unique extraction method allows laboratories to improve their sample processing time by up to 86% by extracting one sample for up to 13...
Measuring Pancreatic Elastase to Diagnose Pancreatic Disease
Many digestive system disorders and diseases can  present similar types of symptoms including bloating, diarrhea, constipation, and weight gain/loss. In an effort to rule in or rule out the presence of one disease or the absence of another, clinicians will often turn to clinically approved stool-bas...
Physiological Actions of Natriuretic Peptides
Introduction Humans have at least 50 discovered hormones managing vital biological functions in the body. These hormones are produced by the body’s organs and glands. Natriuretic peptides (NPs) are structurally related hormones synthesized and released from the heart, including atrial natriuretic p...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...
ALPCO Releases a New Broad Range Periostin ELISA
ALPCO is now offering a new broad range Periostin ELISA that has been optimized to detect all known splicing forms of human periostin. The Periostin ELISA is highly characterized with a full validation package, and offers great reproducibility and precision. Not only are all standards and controls i...
The Changing Roles of Bone Remodeling Biomarkers
Introduction Bones are traditionally known for their support, protection and movement properties, as well as their role in the processes of mineral balance and blood cell production. Research supports that bones do more than they were originally recognized for. Previous research investigating osteo...
Customer Spotlight: Measuring Functionality of Islet Microtissues
Date: July 26, 2016 Beta cell generation has gained much traction in recent years among diabetes researchers. Investigators are not only converting adipose tissue and skin cells into beta cells, they are also starting to grow beta cells in a petri dish in vitro. Swiss company InSphero has begun m...