Company Overview
Accuracy and Efficiency. Together.We are a leading global developer and provider of innovative molecular and immunodiagnostic products focused on Infectious and Gastroenterological Diseases. We are a trusted partner creating value for research and clinical laboratories with high-quality, user-frien...
Responsibility
ALPCO’s Diabetes Research Travel GrantALPCO strives to provide scientists and healthcare professionals with robust tools for their research and clinical diagnostic endeavors. We understand that championing extraordinary discoveries requires extraordinary efforts, and support. We are proud to continu...
Clinical Research
New: Calprotectin Immunoturbidimetric Assay will take your testing to the next level. Learn more.ALPCO has been serving the needs of clinical researchers and clinical diagnostics labs for over 30 years, and we now offer a broad product menu of proprietary automated sample-to-answer platforms. We’re ...
Platforms
Our platforms offer walk-away, sample-to-answer solutions for life science research, clinical research, and diagnosticsALPCO is a global leader in platforms for immunodiagnostics and molecular diagnostics. Our proprietary automated sample-to-answer solutions provide efficiency and ease-of-use for th...
Stool-Based Biomarkers to Differentiate Between IBD and IBS
What are IBD and IBS?
Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are two different gastrointestinal tract issues affecting millions of people every day. Although there is some overlap between symptoms of IBD and IBS, differences still remain in regards to pathologies, risks...
Heart Disease Biomarkers in Diabetes Research
Introduction
Cardiovascular disease (CVD) encompasses a constellation of diseases related to the heart and circulatory system. Despite efforts to understand and combat CVD complications from diabetes, 65% of diabetics will pass away from cardiovascular issues1. Part 2 of The Common Denominator eBoo...
Physiological Actions of Natriuretic Peptides
Introduction
Humans have at least 50 discovered hormones managing vital biological functions in the body. These hormones are produced by the body’s organs and glands. Natriuretic peptides (NPs) are structurally related hormones synthesized and released from the heart, including atrial natriuretic p...
Early Detection of Diabetic Kidney Disease with Biomarkers
Introduction
Over one third of diabetics will develop diabetic kidney disease (DKD) in their lifetime1. Despite the large amount of diabetics suffering from DKD, current methods for measuring and tracking kidney function may not be specific enough for diabetic systems2,3.
Part III of The Common ...
Emerging Biomarker Research in NAFLD and NASH
Nonalcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disease in the western hemisphere affecting 1 in 3 adults and 1 in 10 children1. Today, liver biopsies are the only gold standard for precise diagnosis of NAFLD2. Because of this, there are tremendous efforts on the ...
The Relationship Between Glucagon and Energy Homeostasis
Glucagon is a gut hormone generated as a result of post translational modifications during proglucagon processing in the pancreas1,2,3. Research has demonstrated that glucagon has many physiological functions1,4. Understanding the role of glucagon in energy homeostasis has become important to many d...
ELISAs for CHO Host Cell Proteins
Chinese Hamster Ovary (CHO) cells are the most dependable and most popular host cells for the industrial production of biotherapeutics. They are stable cell lines that are adaptable to a wide range of culture conditions and routinely produce very high protein and antibody yields. More importantly,...
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
Role of IGF-1 in the Growth Hormone/IGF Axis
The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasin...
Toxicology
Drug-Induced Organ Injury
Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in pre...
CisBio's Chromoa® Chromogranin A ELISA
Chromoa®
The Chromoa® Chromogranin A ELISA from Cisbio Bioassays is for the quantitative determination of CgA in serum and plasma. The patented monoclonal detection system provides superior specificity, sensitivity and reproducibility to determine elevated serum CgA levels. Above all, the hook effe...
Understanding the Role of Energy Homeostasis in Diabetes
Introduction
The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and the...
Simplify Stool Sample Processing
Introduction
We understand the challenges facing lab managers and directors who need to continuously improve workflow efficiency and implement new tests and technologies to be competitive. Our unique extraction method can be used with a portfolio of targeted stool markers. This allows your lab to s...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin
Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...
The Significance of Bioactive Leptin in Obesity Research
May 3, 2016
Leptin resistance is a challenging topic of conversation in obesity. It is defined by a state in which the body does not display any adapted response to high endogenous or exogenous levels of leptin while continuing to maintain excess body weight1. This may be due to a decreased uptak...
The Impact of Adiponectin in NAFLD and NASH Research
Date: March 7, 2017
Lately, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) have been widely discussed in both the clinical and research communities. Some of the focus has been related to alternative research methods that can improve diagnostic and monitoring meth...
The Role of Bile Acids in Inflammation
Presented by: Evelyn Zöhrer, PhD; Medical University of Graz
Bile acids act as emulsifiers and promote the absorption of lipids. In addition to the facilitation of digestion, bile acids are now being recognized as key players in the regulation of a myriad of metabolic processes. As such, the role...