GeneProof Molecular Diagnostics Assays & Instrumentation
Manual and automated sample-to-answer solutions for PCR-based molecular diagnostics offering universal protocols, simplified workflows, and a wide range of tests.
myCROBE™ Solution for Extraction, PCR, and automated evaluation of results
The myCROBE Instrument is a fully automated sample-to-answer PCR solution covering the entire nucleic acid extraction and PCR process. Analyze up to 36 samples for up to 10 tests per sample with a maximum of 90 tests per run.
- Sample-to-Answer Testing: on-board nucleic acid extraction, PCR, and automated evaluation of results
- Universal Protocols: mix and match assays and sample types
- Simplified Workflow: ready-to-use reagents and master mix
croGENE Real-Time PCR System
The croGENE Real-Time PCR System is a high-performance, open platform, 6-channel PCR instrument designed for rapid and reliable molecular diagnostics. It supports both qualitative and quantitative analysis and is optimized for use with GeneProof PCR kits. The system features advanced temperature control and a high-sensitivity optical system to ensure accurate and consistent results with capacity for up to 96 samples per run. For Research Use Only. Not for use in diagnostic procedures.
croBEE™ NA16 Nucleic Acid Extraction System Plus
The croBEE™ NA16 Nucleic Acid Extraction System Plus is a compact, fully-automated system for simultaneous nucleic acid extraction from a wide range of biological materials. The extraction principle is based on the nucleic acid binding to paramagnetic particles. A disposable reagent cartridge with all necessary chemical agents ensures simple handling. The extraction process results in high-quality DNA/RNA with highly-reproducible yields. For Research Use Only. Not for use in diagnostic procedures.
croBEE 2.0 Nucleic Acid Extraction System
The croBEE System is a compact, fully automated system for nucleic acid extraction utilizing magnetic separation to generate high-quality DNA and RNA.
- Automated Extraction: generation of high-quality DNA/RNA with highly reproducible yields
- Simplified Workflow: ready-to-use reagents in a convenient disposable cartridge
- Flexible Platform: simultaneous extraction of DNA/RNA from a wide range of sample types
Featured Products for Molecular Diagnostics
-
GeneProof Cytomegalovirus (CMV) PCR Kit$1,200.00We're sorry, an error has occurred while generating this content. -
GeneProof CT/NG/MG Multiplex PCR Kit$1,150.00The GeneProof CT/NG/MG Multiplex PCR Kit detects and distinguishes the most important STI pathogens in a single reaction tube: Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium.
-
GeneProof Human Herpesvirus 8 (HHV-8) PCR Kit$1,200.00We're sorry, an error has occurred while generating this content. -
GeneProof Human Papilloma Virus (HPV) Screening PCR Kit$1,000.00We're sorry, an error has occurred while generating this content.
Explore all of ALPCO’s molecular diagnostics products
Specialty Areas for Molecular Diagnostics Tests
Immunocompromised / Transplanted Infection
Extensive menu for diagnostics and viral load testing in
immunocompromised patients and transplant recipients.
Gastroenterology
Our automated testing solutions provide insights into the digestive system with a growing menu of gastroenterology assays for molecular diagnostics and immunodiagnostics. Get insights for a variety of diseases that affect the intestinal tract.
Infectious Disease
ALPCO offers a wide range of infectious disease assays and products that help scientists understand the interactions between invading microbes and the immune system. Our GeneProof products help detect STIs, respiratory, and blood-borne diseases.
Bloodborne Infections
Mix and match tests for rapid diagnostics and viral load in bloodborne infection
Molecular Diagnostics Resources
Product Portfolio for Molecular Diagnostics of Infectious Diseases
This piece includes a complete listing of PCR and RT-PCR kits for the detection and differentiation of bloodborne, neurological, respiratory, and sexually transmitted infections.
myCROBE Brochure
An overview of the myCROBE Instrument - a fully automated sample-to-answer PCR solution covering the entire nucleic acid extraction and PCR process.
croBEE 2.0 Product Leaflet
The croBEE 2.0 Nucleic Acid Extraction System is a compact, fully automated system designed for time-saving and efficient simultaneous nucleic acid extraction from a wide range of biological materials.
Molecular Testing for Gastrointestinal Pathogens
This flyer offers an overview of the gastrointestinal pathogen PCR / RT-PCR kits available from ALPCO.
Explore all of our molecular diagnostic resources
Resources to advance your discoveries
Recent posts
8 Questions to Ask Before Choosing an Allergy Testing Platform
1. What percentage of your IgE allergy testing panel consists of molecular allergens rather than allergen extracts? The ALEX2 IgE allergen panel consists of 117 extracts and 183 molecular allergens. This represents the largest panel of molecular allergens on the market, including 50 unique...
Understanding IgE Allergy Test Results
Cases of food and environmental allergies have been increasing over the last decade. While conservative estimates suggest IgE-mediated allergy affects 6-8% of children and 2-3% of adults, some estimates are as high as 30%.3, 2 Symptoms can range from mild to severe and include itching, hives,...
Improving Food Elimination Diets with IgG Testing
Food sensitivity or food intolerance involves a non-allergic response to a food or food additive. In a recent on-line survey conducted in the U.S., 24% of adults aged 18 to 79 reported a food intolerance. While a food allergy is typically mediated by IgE antibodies, adverse reactions to food...
Recent posts
An End to Subjective RPR Reading? Development of a Novel Automated Nontreponemal Immunoassay for Syphilis
Discover ALPCO’s novel automated nontreponemal immunoassay for syphilis testing. Reduce subjectivity, improve workflow efficiency, and support faster treatment decisions.
Same Sample, Different Result? What New Research Reveals About Fecal Calprotectin Variability
In a head-to-head comparison of FDA-cleared assays and a novel ALPCO method, investigators observed wide variability in specificity and false-positive rates across platforms, raising important questions about standardization and clinical interpretation.
NuvinkaDx Announces Major Milestones for Portfolio Companies GeneProof and ALPCO
July 22, 2025 – Salem, NH – NuvinkaDx, a leading innovator in diagnostic solutions, today announced two significant product and regulatory milestones from its operating companies, GeneProof and ALPCO.
Biomarkers of Energy Homeostasis Brochure
Energy homeostasis is a focus of research into diabetes and obesity. Read about how our assays in this area can assist both academic and industry researchers.
Complement System Solutions for Drug Development and Clinical Research Datasheet
The complement system is essential to innate immunity from a variety of diseases. ALPCO’s full range of complement system immunoassays can drive discovery.
Melatonin Products for Sleep Disorder-Related Research Datasheet
The melatonin hormone affects the circadian rhythm and sleep-wake cycle. Find out about our immunoassays and products that explore melatonin and sleep disorders.
View our other platforms for life science and clinical solutions
Learn about our solutions for the test that matter most to you
-
IL-6 ELISACatalog #: 04-BI-IL6
Sensitivity: LLOQ: 0.78 pg/ml
Range: 3.125 – 200 pg/mL
Sample Types: Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
Sample Size(s): 100 µL
Detection: Colorimetric -
Vanin-1 ELISA
Catalog #: 04-BI-VAN1U
Sensitivity: 9.6 pmol/l
Range: 37.5-1,200 pmol/l
Sample Types: Urine
Sample Size(s): 10 µL
Detection: Colorimetric -
Aldosterone ELISA
Catalog #: 11-AD2HU-E01
Sensitivity: 9.1 pg/mL
Range: 9.1- 1,000 pg/mL
Sample Types: Plasma, Serum, Urine
Sample Size(s): 50 µL
Detection: Colorimetric -
Cortisol ELISA (Saliva)Catalog #: 11-CORHU-E01-SLV
Sensitivity: 1.0 ng/mL
Range: 1 - 100 ng/mL
Sample Types: Saliva
Sample Size(s): 50 µL
Detection: Colorimetric -
Extraction Columns for Angiotensin/Vasopressin RIA
Catalog #: 12-B-AECX
Sample Types: EDTA Plasma, Urine
Detection: I-125 -
Melatonin Extraction Columns
Catalog #: 12-B-MECX
Sample Types: Biological Fluids, Plasma, Serum, Urine
-
Direct Saliva Melatonin ELISA
Catalog #: 12-EK-DSM-U
Sensitivity: 0.47 pg/mL.
Range: 0.5 - 50 pg/mL
Sample Types: Saliva
Sample Size(s): 200 µL
Detection: Colorimetric -
6-Sulfatoxymelatonin ELISA
Catalog #: 12-EK-M6S-U
Sensitivity: 0.14 ng/mL
Range: 0.8 - 40 ng/mL, adjusted for dilution
Sample Types: Urine
Sample Size(s): 10 µL
Detection: Colorimetric -
Melatonin ELISA
Catalog #: 12-MLTN-96-U
Sensitivity: 0.3 pg/mL
Range: 0.5 - 50 pg/mL
Sample Types: Saliva
Sample Size(s): 100 µL
Detection: Colorimetric -
Plasma/Serum Melatonin ELISA
Catalog #: 12-MLTN-PL-U
Sensitivity: 0.70 pg/mL
Range: 0.70 - 50 pg/mL
Sample Types: Plasma, See Package Insert, Serum, Urine
Sample Size(s): 0.25 mL
Detection: Colorimetric -
Direct Saliva Melatonin RIA
Catalog #: 12-RK-DSM2-U
Sensitivity: 0.9 pg/mL
Range: 0.5 - 50 pg/mL
Sample Types: Saliva
Sample Size(s): 1 mL
Detection: I-125 -
Vasopressin Direct RIA
Catalog #: 12-RK-VPD-U
Sensitivity: 1.3 pg/mL
Range: 1.5 - 100 pg/mL
Sample Types: EDTA Plasma, Urine
Sample Size(s): 400 µL
Detection: I-125