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Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Therapeutic Drug Monitoring of Biosimilars in Autoimmune Diseases
Anti-TNF-alpha biologics have been proven to be effective treatments for autoimmune diseases such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD)1. Rising healthcare costs as well as patent expirations, however, have prompted the development of biosimilars, such as the infliximab b...
ALPCO and InSphero Partner to Offer a Complete Solution to Assess Beta-cell Function in Islet Microtissue Culture Models
July 23, 2018 ALPCO recently announced its partnership with InSphero, AG to provide customers with a complete solution to assess beta-cell function in islet microtissue culture models. InSphero’s 3D InSight™ Diabetes Discovery Platform offers users a comprehensive beta-cell function applic...
An Accurate Solution to the Challenges with Measuring GLP-1
Glucagon-like peptide-1 (GLP-1) is a gut hormone which plays an essential role in insulin secretion and glucose homeostasis1. While GLP-1 has become central to many metabolic disease research programs, various GLP-1 ELISA kits currently available on the market have been failing to meet the needs of ...
The Impact of DPP-4 on Active GLP-1 Preanalytical Variability
Active glucagon-like peptide-1 (active GLP-1) is an incretin hormone known for its pivotal role in the regulation of insulin and glucagon secretion1,2. However, research has demonstrated that the accurate quantification of active GLP-1 is difficult to achieve and has led to the widespread inability ...
How to Properly Collect and Handle GLP-1 Samples
We know that the proper collection and handling of samples is vital for accurately measuring GLP-1. ALPCO is here to help your lab reduce technical errors and improve assay results when running the STELLUX® Chemi Active GLP-1 (7-36) amide ELISA. Watch our video to learn how to properly collect...
12 ELISA Tips and Tricks: An Expert’s Guide to Improve Your Technique
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
How Can Your Lab Benefit from Immunoassay Automation?
The use of the Enzyme-Linked Immunosorbent Assay (ELISA) technique has assisted both clinical and research laboratories in quantifying analytes of interest in heterogeneous samples. The sensitivity and specificity achievable with immunoassays are often ideal for biomarker testing. However, manually ...
Preparing for a Successful Assay Validation
On-boarding of new assays is critical for menu expansion and revenue growth, but the validation of a new assay requires a significant investment of time and resources. Proper planning can reduce errors and delays, minimizing validation time and reducing the impact on normal operations. Below are a f...
The Role of IgE and IgG in Allergy Testing
Cases of food and environmental allergies have been increasing over the last decade. While conservative estimates suggest IgE-mediated allergy affects 6-8% of children and 2-3% of adults, some estimates are as high as 30%.3, 2 Symptoms can range from mild to severe and include itching, hives...
Honoring Scientific Advancements in the Discovery of Insulin
Celebrate Insulin’s Discovery: Download the History of Insulin Timeline for Your Lab! The year 2021 marked the 100th anniversary of Banting, Best, and Macleod discovery of insulin. However, many other scientists also contributed to the foundational understanding of endocrinology that enabled one of ...

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