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New: Calprotectin Immunoturbidimetric Assay will take your testing to the next level. Learn more.Supporting your work with life science and clinical testing productsVIEW ALL LIFE SCIENCE PRODUCTSVIEW ALL CLINICAL DIAGNOSTIC PRODUCTS
Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Responsibility
ALPCO’s Diabetes Research Travel GrantALPCO strives to provide scientists and healthcare professionals with robust tools for their research and clinical diagnostic endeavors. We understand that championing extraordinary discoveries requires extraordinary efforts, and support. We are proud to continu...
Life Science Research
Moving your life science research toward breakthroughs with reagents and walk-away, sample-to-answer solutionsWhether you’re doing basic or translational life science research, you need ready access to the platforms, assays, products, and other tools that are essential to your work. ALPCO has been d...
Differentiating Gastrointestinal Pathogens from IBD and IBS
Gastrointestinal (GI) disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as infections from GI pathogens can present very similar symptoms. A host of tests have been developed to aid in the differentiation between IBD and IBS, such as calprotectin and lact...
Toxicology
Drug-Induced Organ Injury Toxicological side effects are a common obstacle in drug development pipelines and often manifest in site-specific damage to vital organs, including the liver, kidney and heart. Estimates of compound attrition from failure to meet safety endpoints are as high as 45% in pre...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...
Researching Therapeutic Drug Monitoring for IBD
Multiple classes of biologics are available for the treatment of inflammation associated with inflammatory bowel disease (IBD) which ultimately improves the quality of life for patients.  However, many challenges are associated with using biologics to treat IBD such as immunogenetic reactions and th...
Therapeutic Drug Monitoring of Biosimilars in Autoimmune Diseases
Anti-TNF-alpha biologics have been proven to be effective treatments for autoimmune diseases such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD)1. Rising healthcare costs as well as patent expirations, however, have prompted the development of biosimilars, such as the infliximab b...
An Accurate Solution to the Challenges with Measuring GLP-1
Glucagon-like peptide-1 (GLP-1) is a gut hormone which plays an essential role in insulin secretion and glucose homeostasis1. While GLP-1 has become central to many metabolic disease research programs, various GLP-1 ELISA kits currently available on the market have been failing to meet the needs of ...
The Generation and Function of Active GLP-1
The Generation and Function of Active GLP-1 Active glucagon-like peptide-1 (GLP-1) is a member of the incretin hormone family and is generated as a result of post translational modifications during proglucagon processing1,2. Active GLP-1 plays a key role in the incretin effect and is vital for main...
A Guide to STELLUX® Chemiluminscence ELISAs: An Infographic
Today, multiple immunoassay platforms exist, providing scientists and clinicians with the means to measure a variety of biomarkers1,2,3. However, research indicates some immunoassay platforms have limitations that can inhibit progress in the laboratory4,5,6. In an effort to provide researchers with ...
Now Available: 510(k) Cleared Fecal Calprotectin ELISA
ALPCO received 510(k) clearance from the US FDA for its new fecal Calprotectin Chemiluminescence ELISA test. The ALPCO Calprotectin Chemiluminescence ELISA’s superior clinical accuracy will enable clinical laboratories to provide the most accurate results to gastroenterologists facing the cha...
Why Clinical Specificity is Important for FDA Cleared Fecal Calprotectin Tests
The Importance of Clinical Specificity: A Review of FDA Cleared Fecal Calprotectin Tests Download Selecting the right fecal calprotectin test for your clinical laboratory to run in-house or send out can be a difficult task to accomplish, especially when there are multiple FDA cleared options...
Managing Calprotectin as a Send Out?
While sending out for calprotectin testing offers some cost and convenience advantages when volumes are very low, bringing the process in-house allows for the opportunity to control costs, turnaround time, and quality. Considering costs and potential revenue, the volume at which in-house calprotecti...
Enhance Your Lab’s Molecular GI Portfolio
Molecular GI testing for bacteria such as salmonella, vibrio, and E. coli, and viral pathogens including norovirus and rotavirus, is instrumental in the diagnosis and treatment of infection and dysbiosis. In addition, many gastrointestinal disorders often require protein biomarker tests to aid in ac...
GI Testing
Calprotectin Chemiluminescence ELISA (80-CALPHU-CH01) The Calprotectin Chemiluminescence ELISA is an in vitro diagnostic chemiluminescent assay intended for the quantitative measurement of fecal calprotectin, a neutrophilic protein that is a marker of intestinal mucosal inflammation, in human sto...
8 Questions to Ask Before Choosing an Allergy Testing Platform
1. What percentage of your IgE allergy testing panel consists of molecular allergens rather than allergen extracts? The ALEX2 IgE allergen panel consists of 117 extracts and 183 molecular allergens. This represents the largest panel of molecular allergens on the market, including 50+ unique molec...
Real-time PCR/RT-PCR Products for Gastrointestinal Pathogen Detection
Gastrointestinal (GI) pathogens consist of bacterial, viral, and parasitic groups. Bacterial, viral, and parasitic pathogens are caused by direct contact, indirect contact, and contaminated food and water. The most common pathogen is viral, which infects a host by introducing genetic material ...
Immunoassays for Intact and Total Proinsulin
ALPCO is pleased to announce the availability of two new immunoassays, the Intact Proinsulin ELISA and the Total Proinsulin ELISA.  Proinsulin is a precursor molecule produced by pancreatic ß-cells, primarily in response to glucose, that is cleaved equally into insulin and c-peptide. Elevated le...
Featured Biomarkers from A to Z
This handout briefly describes the role of several important hormones measured in research.
ALPCO receives FDA 510(k) clearance for the Calprotectin Immunoturbidimetric Assay
SALEM, NH, June 15, 2023 - American Laboratory Products Company, Ltd. ("ALPCO"), a global provider of specialty diagnostic solutions, today announced recent FDA 510(k) clearance of its Calprotectin Immunoturbidimetric Assay.
AutoPlex Automated Multiplex Biomarker Analysis
ALPCO’s automated multiplex assay, AutoPlex GI Panel, provides sensitive and accurate measurement of up to 5 GI biomarkers in human stool samples. The panel combines the workflow advantages of multiplexing with the proven reliability of traditional chemiluminescence sandwich immunoassays to enable b...
ALPCO Announces the Commercial Launch of its FDA 510(k) Cleared Calprotectin Immunoturbidimetric Assay
Salem, NH, December 19, 2023 – American Laboratory Products Company, Ltd. ("ALPCO"), a global provider of specialty diagnostic solutions, proudly announces the commercial launch of its FDA 510(k) cleared Calprotectin Immunoturbidimetric Assay, enhancing its suite of Gastrointestinal (GI) d...