Tips & Tricks
The Enzyme-Linked Immunosorbent Assay (ELISA) is a proven sensitive method for detecting and quantifying specific biomarkers in a wide range of clinical and research samples. The accuracy and precision of ELISAs can be affected by many factors, including pipetting, washing, and sample-handling techn...
Life Science Research
Moving your life science research toward breakthroughs with reagents and walk-away, sample-to-answer solutionsWhether you’re doing basic or translational life science research, you need ready access to the platforms, assays, products, and other tools that are essential to your work. ALPCO has been d...
TERMS AND CONDITIONS
These Website Standard Terms and Conditions (these “Terms” or these “Website Standard Terms and Conditions”) contained herein on this webpage, shall govern your use of this website, including all pages within this website (collectively referred to herein below as this “Website”). These Terms apply i...
Clinical Research
New: Calprotectin Immunoturbidimetric Assay will take your testing to the next level. Learn more.ALPCO has been serving the needs of clinical researchers and clinical diagnostics labs for over 30 years, and we now offer a broad product menu of proprietary automated sample-to-answer platforms. We’re ...
Investigating Bioactive Leptin in Obesity Research
The Biology of Leptin
Leptin is a hormone composed of 167 amino acids and is primarily produced by adipocytes, therefore providing a signal to the energy state of organisms. By binding to the leptin receptor, the analyte influences activity within the JAK-STAT pathway and thereby regulates energy m...
Role of IGF-1 in the Growth Hormone/IGF Axis
The Growth Hormone/IGF axis consists of IGF-1, IGF-2 and several high and low affinity IGF Binding Proteins (IGFBP). The whole system is tightly regulated by a feedback loop involving Growth Hormone (GH) secreted by the pituitary, and GH production and secretion controlled by Growth Hormone Releasin...
The Changing Roles of Bone Remodeling Biomarkers
Introduction
Bones are traditionally known for their support, protection and movement properties, as well as their role in the processes of mineral balance and blood cell production. Research supports that bones do more than they were originally recognized for. Previous research investigating osteo...
The Impact of DPP-4 on Active GLP-1 Preanalytical Variability
Active glucagon-like peptide-1 (active GLP-1) is an incretin hormone known for its pivotal role in the regulation of insulin and glucagon secretion1,2. However, research has demonstrated that the accurate quantification of active GLP-1 is difficult to achieve and has led to the widespread inability ...
A Comparison of Colorimetric and Chemiluminescence ELISAs
Are you curious about chemiluminescence ELISAs, but not exactly sure what they are, or how to use them? Our video A Comparison of Colorimetric and Chemiluminescence ELISAs discusses how similar these two types of assays are, and how they can enhance your lab testing.
Watch our video to:
Lear...
ALPCO’s Calprotectin Validation Assistance Program
Whether your clinical laboratory is transitioning over to the ALPCO Calprotectin Chemiluminescence ELISA from another calprotectin assay or starting to run the test in-house for the first time, validation is the most crucial step in the assay implementation process. We understand that validating a n...
Diabetes and Obesity
Diabetes and Obesity Learning Library!
As a leading provider of testing solutions for the diabetes and obesity research community, we support scientists’ efforts to gain a greater understanding of these conditions. With no cure for type 1 or type 2 diabetes and a lack of effective obesity treatment...
Preparing for a Successful Assay Validation
On-boarding of new assays is critical for menu expansion and revenue growth, but the validation of a new assay requires a significant investment of time and resources. Proper planning can reduce errors and delays, minimizing validation time and reducing the impact on normal operations. Below are a f...
Vasopressin: An Important Biomarker for Water Metabolism & Sleep Research
ALPCO is pleased to announce the addition of two new radioimmunoassays (RIA) to measure vasopressin. The Vasopressin RIA and the Vasopressin Direct RIA. Both assays were originally developed by BÜHLMANN Laboratories. After optimization for greater ease-of-use, they are now offered by NovoLytiX G...
Immunoassays for Intact and Total Proinsulin
ALPCO is pleased to announce the availability of two new immunoassays, the Intact Proinsulin ELISA and the Total Proinsulin ELISA. Proinsulin is a precursor molecule produced by pancreatic ß-cells, primarily in response to glucose, that is cleaved equally into insulin and c-peptide. Elevated le...
Featured Biomarkers from A to Z
This handout briefly describes the role of several important hormones measured in research.
AACC 2022
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Featuring New and Exclusive Automated Platforms for
Molecular Dx
myCROBE is your PCR Laboratory on the Table
A fully automated sample-to-result solution for molecular diagnos...
Iron Regulation and Homeostasis: Kits to Study Regulatory Proteins
Iron Homeostasis
Iron is a trace element required for several critical cellular processes. Too little iron (anemia) or too much iron (iron overload) can be harmful. While there is no known mechanism for the controlled excretion of excess iron, a handful of regulatory proteins control the absorpti...
Improving Food Elimination Diets with IgG Testing
Food sensitivity or food intolerance involves a non-allergic response to a food or food additive. In a recent on-line survey conducted in the U.S., 24% of adults aged 18 to 79 reported a food intolerance. While a food allergy is typically mediated by IgE antibodies, adverse reactions to food observe...
Celebrating Diabetes Research
In honor of scientists and researchers in the field of diabetes, we've compiled a partial list of their 2023 published work. These publications aren't just studies; they're milestones on the path to a healthier future, made possible by their dedication.
What makes this list so ...