Vitamin D Binding Protein ELISA
Vitamin D Binding Protein ELISA is an enzyme immunoassay intended for the quantitative determination of free and not actin complex bound vitamin D binding protein in human serum, plasma and urine.
- Includes standards and controls
- Short incubation time of 2 hours and 20 minutes
- Colorimetric Detection
For research use only. Not for use in Diagnostic Procedures.
Vitamin D binding protein (VDBP, also known as group-specific component / Gc protein) is a multifunctional serum protein which is formed in the liver. High estrogen levels, caused e. g. by pregnancy or hormonal birth control, stimulate its synthesis. VDBP can be found in plasma, ascites, liquor, urine and at the surface of various cell types.
In the blood, VDBP binds the bigger part of the circulating 25-OH vitamin D and brings it to the kidneys, where it is transformed into the hormone 1,25-(OH)2 vitamin D. VDBP binds to monomeric actin at the ratio of 1:1 and is a precursor of the immunomodulating protein Gc protein-derived macrophage activating factor (Gc-MAF).
Research area interests include sepsis, trauma, organ failure, Nephritic syndrome, and Tumors.