Bovine Haptoglobin ELISA

$604.00
Catalog
41-HAPBO-E01
The Bovine Haptoglobin ELISA is for the determination of Haptoglobin in Serum or Plasma of cattle. Research Use Only. Not for Use in Diagnostic Procedures.
Species
Bovine
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available Worldwide
Range
15.6 - 1,000 ng/mL
Sensitivity
15.6 ng/mL
Sizes
96 Wells
Sample Types
Plasma, Serum
Inc Time Minute
40
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
5
Detection
Colorimetric
Acute phase proteins are plasma proteins which increase in concentration following infection, inflammation or trauma. The first acute phase protein to be recognized was discovered in humans by Tillet and Frances in 19301 . Haptoglobin (Hp) is a heterogeneous plasma protein mostly synthesized by the liver. The haptoglobin monomer consist of two heavy chains, beta chains (40 kD) and two light chains, alpha chains, alpha 1 (9 kD) and alpha 2 (16 kD) that are linked disulfide bonds. The three major haptoglobin types are; Hp1-1 which is monomeric (98kD), Hp1-2 is polymeric at about 200 kD, and Hp2-2 at about 400 kD. The levels in serum rise quickly following acute tissue damage within 24 to 48 hours and also fall very rapidly once the stimulus is removed. In fact, Hp levels are decreased in hemolytic anemia. Hp has a high affinity for hemoglobin (Hb) and its function appears to be to prevent loss of Hb in urine which would lead to loss of iron. Investigations over the past few years have shown that quantification of Hp in plasma or serum can provide valuable research information on the detection, prognosis, and monitoring of disease not only in humans, but in companion animals and farm herds as well2 .

Bovine Haptoglobin ELISA

41-HAPBO-E01

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