The Alpha 1 Microglobulin ELISA is for the quantitative determination of alpha-1-Microglobulin in Serum, Plasma and Urine. For research use only. Not for use in diagnostic procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
0.019 - 1.5 mg/L
Sensitivity
0.006 mg/L
Sizes
96 Wells
Sample Types
Plasma, Serum, Urine
Inc Time Hour
4
Inc Time Minute
45
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
10
Detection
Colorimetric
Alpha 1 Microglobulin, a glycoprotein heterogeneous in charge, was reported to occur both as a monomer with 31kDa but also as a polymer with 90 kDa in a covalent binding with one of the two alpha chains of the monomeric Immunoglobulin A. Alpha-1-Mikroglobulin is produced in the liver and is a protein with a small molecular weight. These proteins are metabolised in the kidneys and in a healthy person, only minor amounts can be detected in urine. If the glomerular filtration rate is limited, then the increase of Alpha-1-Microglobulin is seen in serum. If the relationship between the total sum of Albumin-IgG, Alpha-1-Microglobulin in comparison to the total protein in urine is disturbed, then this indicates a prerenal protinuria.
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