Glutathion-S-Transferase Activity Assay (GST Activity Assay)
$755.00
Catalog
30-2631
Glutathion-S-Transferase Activity Assay (GST Activity Assay)
Species
Human
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
see package insert
Sensitivity
see package insert
Sizes
100 Tests
Sample Types
Biological Fluids
Inc Time Hour
1
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
100
Glutathione-S-transferases (GSTs) are a group of enzymes that are important in the detoxication of many different xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity was found to be present in plants, insects, yeast, bacteria, and in most mammalian tissues, especially in the liver, which plays a key role in detoxification. There are several classes of GST isoenzymes that differ in their specificity toward xenobiotic or endogenous substrates.
The Glutathion-S-Transferase Activity Assay (GST Activity Assay) utilizes 1-Chloro-2,4- dinitrobenzene (CDNB) which is suitable for the broadest range of GST isoenzymes. Upon conjugation of the thiol group of glutathione to the CDNB substrate, there is an increase in the absorbance at 340 nm.
The Glutathion-S-Transferase Activity Assay (GST Activity Assay) is for Research Use Only.
For more information on the Glutathion-S-Transferase Activity Assay (GST Activity Assay), call 800-592-5726.
The Glutathion-S-Transferase Activity Assay (GST Activity Assay) utilizes 1-Chloro-2,4- dinitrobenzene (CDNB) which is suitable for the broadest range of GST isoenzymes. Upon conjugation of the thiol group of glutathione to the CDNB substrate, there is an increase in the absorbance at 340 nm.
The Glutathion-S-Transferase Activity Assay (GST Activity Assay) is for Research Use Only.
For more information on the Glutathion-S-Transferase Activity Assay (GST Activity Assay), call 800-592-5726.
