Zonulin Stool ELISA
This ELISA is intended for the quantitative determination of zonulin family peptides (ZFP) in stool.
For research use only. Not for use in diagnostic procedures.
The polyclonal anti-body used in this ELISA is based on the zonulin sequence as published by Wang (Journal of Cell Science, 2000) and di Pierro (Journal of Biological Chemistry, 2001).
Zonulin is a human protein analogue to the zonula occludens toxin derived from Vibrio cholerae which regulates tight junctions of the digestive tract. Zonulin binds to a specific receptor on the surface of intestinal epithelia and triggers a cascade of biochemical events which induces tight junction disassembly and a subsequent permeability increase of the intestinal epithelia, allowing some substances to pass through and activate immune reactions.