TGF Beta-1 ELISA
$814.00
Catalog
20-TGF1HU-E01
The TGF-β1 ELISA is an enzyme immunoassay for the quantitative in vitro diagnostic measurement of TGF-β1 in serum and cell culture supernatant. FDA Registered. For In Vitro Diagnostic Use.
Transforming Growth Factor β1 (TGF-β1) is a 25 kDa homodimer composed of two 12.5 kDasubunits joined by disulfide bonds (1). TGF-β1 is a multipotent cytokine with cell- and dosedependent activities. This molecule is produced by a number of cells and tissue types, e.g.thrombocytes, bone tissue, placenta and kidneys. This potent cytokine modulates embryonicdevelopment, bone formation, mammary development, wound healing, hematopoiesis, cell cycleprogression and the production of the extracellular matrix. With respect to the immune system,TGF-β1 inhibits T and B cell proliferation and acts as an anti-inflammatory molecule both in vitroand in vivo. TGF-β1 inhibits macrophage maturation and activation. This molecule also inhibitsthe activity of natural killer cells and lymphokine activated killer cells and blocks cytokineproduction.
Species
Human
Regulatory Status
FDA Registered. For In Vitro Diagnostic Use.
Product Distribution
Available Worldwide
Range
19 - 600 pg/mL
Sensitivity
1.9 pg/mL
Sizes
96 Wells
Sample Types
Cell Culture, Serum
Inc Time Hour
6
Inc Time Minute
45
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
10
Detection
Colorimetric
