Sclerostin ELISA

$693.00
Catalog
04-BI-20492

The Sclerostin ELISA is intended for the quantitative determination of sclerostin in Human serum, EDTA plasma or heparin plasma.

  • Includes controls and standards
  • Small sample volume requirement: 20 µL
  • Colorimetric Detection
  • Excellent precision and reproducibility
  • Intra-assay CV 7%
  • Inter-assay CV 10%

For Research Use Only. Not for Use in Diagnostic Procedures.

Species
Human
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
15-240 pM
Sensitivity
2.6 pM
Sizes
96 Wells
Sample Types
EDTA Plasma, Heparin Plasma, Serum
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
20
Detection
Colorimetric

Sclerostin (SOST) is a 22.5 kD secreted glycoprotein produced in osteocytes and is considered a highly specific biomarker for bone. SOST inhibits osteoblast activity via antagonism of the Wnt Signaling pathway and plays a key role in the regulation of bone formation.

SOST levels are of interest in many research fields including bone metabolic diseases, multiple myeloma, chronic kidney disease, type 2 diabetes, and chronic inflammation.

Sclerostin ELISA

04-BI-20492

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