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AGA Guidelines: Calprotectin and C-Reactive Protein Monitoring for the Management of Crohn’s Disease


Download ou infograhpic prepared by ALPCO and gain a comprehensive overview of the American Gastroenterological Association (AGA)  guidelines, offering a new perspective on managing Crohn's Disease using biomarkers.


Key highlights include the guideline panel's 11 conditional recommendations, particularly focusing on the use of a biomarker- and symptom-based monitoring strategy. It clarifies the significance of fecal calprotectin and CRP levels in assessing disease activity and guiding the need for endoscopic evaluation.  



[Infographic] Biomarker Monitoring for the Management of Crohn’s Disease

Important products for Gastroenterology 

Spotlight: Immunoturbidimetric Assay for Fecal Calprotectin

Extraction to Results – Simplify Complexity

Leverage the power of our FDA-Cleared Immunoturbidimetric (IT) Assay for fecal calprotectin designed to integrate seamlessly with your existing clinical chemistry analyzer. Experience a method that is not only time and cost-efficient but also a viable alternative to conventional and send-out methodologies.

Get your time backGet your time back


Upgrading to ALPCO’s Immunoturbidimetric solution for calprotectin testing offers a 40%-65% reduction in time to first result compared to leading Flash Chemiluminescence automated systems.



ALPCO’s Calprotectin IT Assay combines the clinical sensitivity and specificity clinicians expect with the efficiency and repeatability today’s laboratories require.

Maximize ThroughputMaximize Throughput


Increase throughput by more than 57% when comparing tests per hour from a leading CLIA system to ALPCO’s Immunoturbidimetric assay running on a clinical chemistry analyzer.

Cost savingsCost savings


Realize a savings of up to 87% on the cost per test when comparing the average send-out cost to ALPCO’s in-house cost per test.

Ready to Schedule Your Free Evaluation?

See for yourself why labs are switching to ALPCO’s new FDA-cleared Calprotectin Immunoturbidimetric Assay.

One free kit per laboratory. Void where prohibited.

Simplicity, Efficiency, and Cost Effectiveness, All While Elevating Confidence in Your Results.


  • The calprotectin immunoturbidimetric assay (80-CALPHU-IT200, -100) is 510(k)-cleared in the U.S., IVDD in the EU, and has been submitted for review by Health Canada.

  • It is recommended to run calibrators once per month and with every kit lot change. Two controls are typically run each day calprotectin testing is performed.

  • Unlike traditional ELISA, which could have up to 22 non-reportables per run (8 calibrators and 3 controls in duplicate), the immunoturbidimetric assay requires only two non-reportables (2 controls) per day, easily accommodating low volume to high volume testing at a competitive cost per test.

ALPCO Gastroenterology Resources to Advance Your Discoveries 

Differentiating IBD from IBS with Fecal Calprotectin Testing

In an effort to improve patient care, an increasing number of gastroenterologists are using fecal calprotectin levels as a first step in the diagnosis of IBD versus IBS.


Diagnostic Testing in GI Health

60 to 70 million Americans are affected by gastrointestinal (GI) diseases and disorders each year. The estimated annual U.S. cost associated with GI disorders is over 140 billion dollars. Gl diseases and disorders can have a significant impact on quality of life, often contributing to anxiety and depression.


ALPCO's Superior Calprotectin Assay: Maximize Efficiency & Accuracy

Automate on Your Current Analyzer Without Sacrificing Clinical Sensitivity or Specificity




Consolidate and Improve Calprotectin Testing on Clinical Chemistry Analyzers with ALPCO

Testing Fecal Calprotectin on a CLIA System? Consolidate Testing with the Calprotectin Immunoturbidimetric Assay.



Boost Profitability with In-House Calprotectin Testing from ALPCO

For laboratories with a compatible clinical chemistry analyzer, on-boarding of the calprotectin immunoturbidimetric assay is simple.



High Throughput Calprotectin Testing with ALPCO Immunoturbidimetric Assay

With clinical sensitivity of 91% and clinical specificity of 93%, the ALPCO calprotectin immunoturbidimetric assay offers the efficiency of automation without sacrificing clinical performance. 


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