The Pepsinogen I ELISA is an enzyme immunoassay for the quantitative determination of human pepsinogen I levels in Serum. Research Use Only. Not for Use in Diagnostic Procedures.
Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular
weight of 42 kDa. Pepsinogen I is synthesized at gastric chief cells and mucous neck cells, while
pepsinogen II is produced not only by gastric chief cells and mucous neck cells, but also by clear
mucous cells of antrum, etc. The research applications of measuring pepsinogen I and
pepsinogen II include studying severe atrophic gastritis and stomach cancer. Research has
suggested that the measurement of serum pepsinogens may serve as a “serological biopsy” for
predicting the presence of atrophic gastritis or superficial gastritis.
1. What percentage of your IgE allergy testing panel consists of molecular allergens rather than allergen extracts? The ALEX2 IgE allergen panel consists of 117 extracts and 183 molecular allergens. This represents the largest panel of molecular allergens on the market, including 50 unique...
Cases of food and environmental allergies have been increasing over the last decade. While conservative estimates suggest IgE-mediated allergy affects 6-8% of children and 2-3% of adults, some estimates are as high as 30%.3, 2 Symptoms can range from mild to severe and include itching, hives,...
Food sensitivity or food intolerance involves a non-allergic response to a food or food additive. In a recent on-line survey conducted in the U.S., 24% of adults aged 18 to 79 reported a food intolerance. While a food allergy is typically mediated by IgE antibodies, adverse reactions to food...
In a head-to-head comparison of FDA-cleared assays and a novel ALPCO method, investigators observed wide variability in specificity and false-positive rates across platforms, raising important questions about standardization and clinical interpretation.
July 22, 2025 – Salem, NH – NuvinkaDx, a leading innovator in diagnostic solutions, today announced two significant product and regulatory milestones from its operating companies, GeneProof and ALPCO.
Energy homeostasis is a focus of research into diabetes and obesity. Read about how our assays in this area can assist both academic and industry researchers.
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