Osteocalcin Immunoradiometric Assay (IRMA) for the determination of osteocalcin in human serum and plasma samples. Research Use Only. Not for Use in Diagnostic Procedures. Replacement for osteocalcin RIA 72-OSTEO-CT-US.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in USA Only
Range
1.9 - 69 ng/mL
Sensitivity
0.22 ng/mL
Sizes
96 Tests
Sample Types
Plasma, Serum
Inc Time Hour
2
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
50
Detection
I-125
Osteocalcin or bone Gla protein (B.G.P) is the major non-collagen protein of the bone matrix. It has a molecular weight of 5800 Da and contains 49 amino acids, including 3 residues of gamma carboxyl glutamic acid. Osteocalcin is synthesized in the bone by the osteoblasts. After production, it is partly incorporated in the bone matrix and the rest is found in the blood circulation. The exact physiological function of osteocalcin is still unclear. A large number of studies show that the circulating levels of osteocalcin reflect the rate of bone formation.
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