Leptin Receptor ELISA is for the quantitative determination of human leptin receptor in
in human serum, plasma, and culture supernatant. Research Use Only. Not for Use in Diagnostic Procedures.
Leptin receptor (OB-R) was identified as a leptin binding protein (Leptin, the product of the ob gene, is a single-chain 16 kDa protein consisting of 146 amino acid residues.) OB-R was found to be a member of the class I cytokine receptor family with a large extracellular domain comprising 816 amino acid residues. Leptin receptor exists in multiple forms with a common extracellular domain and a variable length cytoplasmatic portion. Alternate splicing from a single gene derives the six isoforms of the Leptin receptor. The soluble form of the Leptin receptor, OB-R, contains no intracellular motifs or transmembrane residues; thus, it consists entirely of the extracellular ligand-binding domain of the receptor
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
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