The Intact Osteocalcin ELISA is for the quantitative determination of intact Osteocalcin in serum. Osteocalcin is an important biomarker for the measurement of bone formation and resorption - high levels of circulating osteocalcin are associated with increased bone turnover. Research Use Only. Not for Use in Diagnostic Procedures.
Osteocalcin or bone Gla protein (B.G.P) is the major non-collagen protein of the bone matrix. It
has a molecular weight of 5800 Da and contains 49 amino-acids, including 3 residues of gammacarboxyl-glutamic acid. Osteocalcin is synthesized in the bone by the osteoblasts. After
production, it is partly incorporated in the bone matrix and the rest is found in the blood circulation.
The exact physiological function of osteocalcin is still unclear. A large number of studies show
that the circulating levels of osteocalcin reflect the rate of bone formation.
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Cases of food and environmental allergies have been increasing over the last decade. While conservative estimates suggest IgE-mediated allergy affects 6-8% of children and 2-3% of adults, some estimates are as high as 30%.3, 2 Symptoms can range from mild to severe and include itching, hives,...
Food sensitivity or food intolerance involves a non-allergic response to a food or food additive. In a recent on-line survey conducted in the U.S., 24% of adults aged 18 to 79 reported a food intolerance. While a food allergy is typically mediated by IgE antibodies, adverse reactions to food...
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July 22, 2025 – Salem, NH – NuvinkaDx, a leading innovator in diagnostic solutions, today announced two significant product and regulatory milestones from its operating companies, GeneProof and ALPCO.
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