Free Soluble RANKL High Sensitivity ELISA
The Free Soluble RANKL ELISA for the quantitative determination of free, soluble and uncomplexed human RANKL in serum and heparin plasma.
- High sensitivity: 0.01 pmol/L
- Includes controls and standards
- Excellent precision and reproducibility:
- Intra-Assay CV= 4%
- Inter-Assay CV= 2-3%
- Colorimetric Detection
For Research Use Only. Not for Use in Diagnostic Procedures.
Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) is a transmembrane protein produced by osteocytes and is part of the tumor necrosis factor (TNF) family. It is the main stimulant for osteoclast formation and is essential for their survival. RANKL expression leads to bone reabsorption and loss which is counteracted by osteoprotegerin (OPG). RANKL/OPG system regulates bone remodeling and an imbalance may lead to bone metabolic diseases.
Research interests include bone remodleing, immunology, bone metastasis in cancer, thermoregulation, and type 2 diabates.