Myeloperoxidase ELISA (MPO ELISA)

$481.00
Catalog
30-6630

Myeloperoxidase ELISA (MPO ELISA) is intended for the quantitative determination of MPO in human stool and urine.

  • Includes standards and controls
  • Incubation time is less than 4 hours
  • No cross reactivity to other proteins in stool such as Albumin, CRP, Calprotectin, and Lysozyme

For research use only. Not for use in diagnostic procedures.

Species
Human
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
1.2 - 100 ng/mL
Sensitivity
1.6 ng/mL
Sizes
96 Wells
Sample Types
Stool, Urine
Inc Time Hour
2
Inc Time Minute
20
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
100
Detection
Colorimetric

MPO is a Leukocyte inflammatory protein that is part of very strong anti-microbial system. In the anti-microbial system, MPO, hydrogen peroxide, and a halogen together generate Reactive Oxygen Species (ROS) to digest foreign invaders such as bacteria, fungi, viruses and mycoplasma. PMN-Elastase can increase the MPO-H2O2's effencenty at destorying bacterial invaders.

If a cell’s antioxidative defense system fails, ROS can leak into extra-cellular space, inhibit leukocyte function, and damage cells. The MPO defense system can be inhibited by catalase, excess of hydrogen peroxide and other reducing substances.

MPO determination in the stool can help research the inflammatory activity of Crohn´s disease or ulcerative colitis. Other research area interests include inflammation, oxidative health, initiation and progression of CVD, myocardial infarction, and diabetes.

Myeloperoxidase ELISA (MPO ELISA)

30-6630

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