17-alpha Hydroxy Progesterone ELISA

$335.00
Catalog
20-17OHU-E01

The 17-alpha Hydroxy Progesterone ELISA is for the quantitative determination of 17-alpha Hydroxy Progesterone in Serum.

FDA Registered. For In Vitro Diagnostic Use in the United States.
Species
Human
Regulatory Status
FDA Registered. For In Vitro Diagnostic Use.
Product Distribution
Available Worldwide
Range
0.15 - 20 ng/mL
Sensitivity
0.083 ng/mL
Sizes
96 Wells
Sample Types
Serum
Inc Time Hour
1
Inc Time Minute
35
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
25
Detection
Colorimetric
The steroid 17-α-hydroxyprogesterone (17-α-OHP) is produced by both the adrenal cortex and gonads. Even though 17-α-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-deoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-α-OHP, measurement of 17-α-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17-α-OHP is secreted in abundant excess. It is moderately elevated in 11-β-hydroxylase deficiency as well. Measurement of 17-α-OHP is therefore valuable in the initial diagnosis of CAH.

17-alpha Hydroxy Progesterone ELISA

20-17OHU-E01

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