Therapeutic Drug Monitoring of Biologics in IBD
Biologics, such as TNF-α and integrin blockers, have been used to treat inflammatory bowel disease (IBD) for several years. Therapeutic drug monitoring assays can measure the drug level and anti-drug antibody (ADA) level of biologics including Adalimumab, Infliximab, Golimumab, Vedolizumab, and Ustekinumab.. Drug level and ADA measurements can determine if primary non-response (PNR) is occurring, and can also predict and define loss of response (LOR) to the biologic.
Our therapeutic drug monitoring panel includes ELISAs for testing response to the commonly used biologics Adalimumab, Infliximab, Golimumab, Vedolizumab. and Ustekinumab.