Alpco assay

Osteocalcin (1-43/49) ELISA

ALPCO Catalog Number: 43-OSNHU-E01

Osteocalcin (1-43/49) ELISA

For Research Use Only This item appears in:  Format:  ELISA / EIA  Sample Type: Serum, Plasma  Sample Size: 25 µl  Size:  96 Wells  Range:  0 - 64 ng/ml  Sensitivity:  0.31 ng/ml  Incubation Time:  1 Hour 20 Min  Protocol:    Download Protocol   (244 KB) International Distribution:  Available worldwide.  Price:   Related Products:

This ELISA uses a two-site sandwich antibody technique to specifically measure both the intact (1-49) and n-terminal mid-fragment (1-43) circulating forms of osteocalcin in human Serum and Plasma.

Intact osteocalcin is prone to degradation, both endogenously and after sample collection; the 1-43 fragment is more stable than the intact molecule, making the combined measurement less susceptible to differences caused by degradation of the intact molecule over time (as well as controlling for differences in sample processing and handling).

In addtion, the ratio of the fragment (1-43) to intact (1-49) may differ from sample to sample, so measuring the total pool may be more meaningful from a physiological standpoint.

Special Introductory Pricing Available - Contact ALPCO at 1-800-592-5726, or your local distributor, for details!

Tags

osteocalcin, bone, intact osteocalcin, N-MID osteocalcin