Alpco ELISA

Cathepsin K ELISA

ALPCO Catalog Number: 04-BI-20432

Cathepsin K ELISA

For Research Use Only This item appears in: Bone Metabolism  Format:  ELISA / EIA  Sample Type: Serum, Cell Culture  Sample Size: 50 µl  Size:  96 Wells  Range:  11 - 300 pmol/L  Sensitivity:  1.1 pmol/l  Incubation Time:  Overnight  Protocol:    Download Protocol   (403 KB) International Distribution:  Only available in North America  Price:   Related Products:

The Cathepsin K ELISA is an enzyme immunoassay intended for the quantitative determination of human Cathepsin K in Serum or Cell Culture supernatants. Cathepsin K is a cysteine protease secreted by osteoclasts, and because it degrades the collagen matrix of the bone after removal of its mineral components, it plays a key role in tissue destruction, remodelling and cartilage breakdown. The high homology of Cathepsin K across various species (mouse 86%, rat 88%, pig 97%, rabbit 96%) allows for the use of this assay in humans and in animal models for the study of bone turnover, osteoporosis and inflammatory processes affecting the skeleton.

Tags

Cathepsin K ELISA, Bone and Mineral Metabolism, 004-BI-20432