For Research Use Only

 

Summary:

Chemerin, also known as tazarotene-induced gene 2 (TIG2) or retinoic acid receptor responder 2 (RARRES2), is synthesized as precursor protein of 163 amino acids including a N-terminal signal peptide of 20 amino acids, which is chipped of enduring secretion. The inactive, circulation proform of Chemerin contains six cystein residues and thus three intramolecular disulfide bridges are suggested.

For the further investigation of Chemerin functions and its quality as biomarker in metabolic diseases reliable measurement of Chemerin in different body fluids is a prerequisite. ALPCO offers a sensitive and reproducible test system for the quantitative measurement of Chemerin. Based on highly specific antibodies total Chemerin is measured.